InterPro domain: IPR044653

This entry represents a group of plant Cys2/His2 (C2H2)-type zinc-finger proteins, including AZF1/2/3 and ZAT6/10 from Arabidopsis. They belong to the C1-2i subclass of zinc-finger proteins in Arabidopsis [ 1 ]. In general they function as transcription repressors under drought, cold, and high-salinity stress conditions [ 2 ]. AZF1 and AZF2 have been shown to negatively regulate abscisic acid-repressive and auxin-inducible genes under abiotic stress conditions [ 3 ]. ZAT6 has been shown to regulate root development and nutrient stress responses [ 4 ].

1. The Roles of Arabidopsis C1-2i Subclass of C2H2-type Zinc-Finger Transcription Factors. Genes (Basel) 10, 2734-46
2. Arabidopsis Cys2/His2-type zinc-finger proteins function as transcription repressors under drought, cold, and high-salinity stress conditions. Plant Physiol 136, 147-59
3. Arabidopsis Cys2/His2 zinc-finger proteins AZF1 and AZF2 negatively regulate abscisic acid-repressive and auxin-inducible genes under abiotic stress conditions. Plant Physiol 157, 742-56
4. Phosphate homeostasis and root development in Arabidopsis are synchronized by the zinc finger transcription factor ZAT6. Plant Physiol 145