InterPro domain: IPR044645

This entry represents a group of chloroplastic pentatricopeptide repeat-containing proteins, including DG1 (At5g67570) and EMB2279 (At1g30610) from Arabidopsis. DG1 is involved in the regulation of early chloroplast development and chloroplast gene expression [ 1 ]. DG1 mutants have pale young leave and reduced accumulation of plastid encoded transcripts [ 2 ]. DG1 has been shown to interact with SIG6, a chloroplast sigma factor responsible for the transcription of plastid-encoded RNA polymerase (PEP) dependent chloroplast genes in cotyledons [ 2 ]. DG1 plays an important role in maintaining chloroplast mRNA editing [ 3 ]. EMB2279 is required for intron splicing of plastid rpl2 and trnK. Mutations in the EMB2279 gene result in embryo lethality due to defects in chloroplast development [ 4 ].

1. The pentratricopeptide repeat protein DELAYED GREENING1 is involved in the regulation of early chloroplast development and chloroplast gene expression in Arabidopsis. Plant Physiol 147, 573-84
2. Interaction of the pentatricopeptide-repeat protein DELAYED GREENING 1 with sigma factor SIG6 in the regulation of chloroplast gene expression in Arabidopsis cotyledons. Plant J 64, 14-25
3. Mutation of DELAYED GREENING1 impairs chloroplast RNA editing at elevated ambient temperature in Arabidopsis. J Genet Genomics 47, 201-212
4. The Pentatricopeptide Repeat Protein SOT5/EMB2279 Is Required for Plastid rpl2 and trnK Intron Splicing. Plant Physiol 177, 684-697