InterPro domain: IPR044287

General Information

  • Identifier IPR044287
  • Description Protein SUPPRESSOR OF GENE SILENCING 3
  • Number of genes 272
  • Gene duplication stats Loading...
  • Associated GO terms GO:0031047   GO:0051607  

Abstract

This entry represents a group of plant proteins, including Protein SUPPRESSOR OF GENE SILENCING 3 (SGS3) from Arabidopsis. Post-transcriptional gene silencing (PTGS) in plants requires at least two proteins-SGS3 and MET1 (a DNA-methyltransferase) [ 1 , 2 ]. SGS3 is required for juvenile development and the production of trans-acting siRNAs [ 3 ]. SGS3 is also involved in a mechanism for plant resistance to viruses [ 4 , 4 ].


1. Post-transcriptional gene silencing in plants. J Cell Sci 114, 3083-91
2. Geminivirus VIGS of endogenous genes requires SGS2/SDE1 and SGS3 and defines a new branch in the genetic pathway for silencing in plants. Plant J. 38, 1004-14
3. SGS3 and SGS2/SDE1/RDR6 are required for juvenile development and the production of trans-acting siRNAs in Arabidopsis. Genes Dev. 18, 2368-79

Species distribution

Gene table