InterPro domain: IPR044231

General Information

  • Identifier IPR044231
  • Description E3 ubiquitin-protein ligase SP1-like
  • Number of genes 211
  • Gene duplication stats Loading...
  • Associated GO terms GO:0004842   GO:0016567  

Abstract

This entry represents a group of E3 ubiquitin-protein ligases, including SP1 and SPL1 from Arabidopsis. They are E3 ubiquitin-protein ligases involved in the regulation of protein import in the chloroplast [ 1 ]. SP1 is associated with TOC (translocon at the outer envelope of chloroplasts) complexes and can mediate ubiquitination of TOC components, promoting their degradation [ 2 ].

This entry also includes some uncharacterised bacterial proteins.


1. Regulation of Chloroplast Protein Import by the Ubiquitin E3 Ligase SP1 Is Important for Stress Tolerance in Plants. Curr. Biol. 25, 2527-34
2. Chloroplast biogenesis is regulated by direct action of the ubiquitin-proteasome system. Science 338, 655-9

Species distribution

Gene table