InterPro domain: IPR044227

General Information

  • Identifier IPR044227
  • Description Protein TONSOKU

Abstract

TONSOKU (also known as MGOUN3 or BRUSHY1 (BRU1)) is a nuclear leucine-glycine-asparagine (LGN) domain protein that links responses to DNA damage and epigenetic gene silencing in Arabidopsis. Mutants with defects in TONSOKU display a fasciated stem and disorganized meristem structures [ 1 ]. TONSOKU is specifically expressed during S phase and acts with GIP1 synergistically for the maintenance of centromeric cohesion [ 2 ].


1. MGOUN3: evidence for chromatin-mediated regulation of FLC expression. J. Exp. Bot. 57, 2111-9
2. MGO3 and GIP1 act synergistically for the maintenance of centromeric cohesion. Nucleus 8, 98-105

Species distribution

Gene table