InterPro domain: IPR039928
General Information
- Identifier IPR039928
- Description LNK family
- Number of genes 499
- Gene duplication stats Loading...
- Associated GO terms GO:0006355 GO:0007623
Abstract
The LNK family consists of light and clock regulated morning genes from plants. These control both the pace of circadian rhythms and the photoperiodic regulation of flowering time by promoting the expression of a subset of clock and flowering time genes in the afternoon [ 1 ]. The LCL domain of clock-related factor REVEILLE8 recruits LNKs to target promoters, while its MYB domain provides DNA binding specificity. In turn, LNKs interact with RNA Polymerase II and the transcript elongation FACT complex, resulting in rhythmic changes of gene expression [ 2 ].
1. LNK genes integrate light and clock signaling networks at the core of the Arabidopsis oscillator. Proc. Natl. Acad. Sci. U.S.A. 110, 12120-5
2. Targeted Recruitment of the Basal Transcriptional Machinery by LNK Clock Components Controls the Circadian Rhythms of Nascent RNAs in Arabidopsis. Plant Cell 30, 907-924