InterPro domain: IPR039182

General Information

  • Identifier IPR039182
  • Description Ribonucleases P/MRP protein subunit Pop1

Abstract

Pop1 is a component of ribonuclease P, a ribonucleoprotein enzyme that cleaves precursor tRNA transcripts to give mature 5' ends. It is also a component of RNase MRP [ 1 , 2 , 3 ].


1. The POP1 gene encodes a protein component common to the RNase MRP and RNase P ribonucleoproteins. Genes Dev. 8, 1423-33
2. Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRP. Genes Dev. 12, 1678-90
3. Cryo-EM Structure of the Human Ribonuclease P Holoenzyme. Cell 175, 1393-1404.e11

Species distribution

Gene table