InterPro domain: IPR035261

General Information

  • Identifier IPR035261
  • Description 26S proteasome regulatory subunit 8
  • Number of genes 264
  • Gene duplication stats Loading...
  • Associated GO terms GO:0036402  

Abstract

This entry represents regulatory subunit 8 (gene name PSMC5 or Rpt6) of the 26S proteasome, which is a component of the 19S proteasome cap [ 1 ]. PSMC5 is one of the ATPases that form a heterohexameric ring for unfolding ubiquitinated proteins targeted for degradation by the proteasome.


1. Structure of the human 26S proteasome at a resolution of 3.9 A. Proc. Natl. Acad. Sci. U.S.A. 113, 7816-21

Species distribution

Gene table