InterPro domain: IPR034772

General Information

  • Identifier IPR034772
  • Description CPSF6/7 family
  • Number of genes 271
  • Gene duplication stats Loading...

Abstract

This entry includes cleavage and polyadenylation specificity factor subunit 6/7 (CPSF6/7) from mammals and CG7185 from Drosophila melanogaster. This entry also includes proteins from fungi and plants. CPSF6/7 are components of the Cleavage Factor Im complex (CFIm) which plays a key role in pre-mRNA 3'-cleavage and polyadenylation [ 1 ].


1. The Cleavage and Polyadenylation Specificity Factor 6 (CPSF6) Subunit of the Capsid-recruited Pre-messenger RNA Cleavage Factor I (CFIm) Complex Mediates HIV-1 Integration into Genes. J. Biol. Chem. 291, 11809-19

Species distribution

Gene table