InterPro domain: IPR032710

This superfamily represents a domain covering the whole length of the nuclear transport factor 2 (NTF2). It has a beta-alpha(2)-beta insertion after the main helix. Ntf2 protein is a nuclear envelope protein facilitating protein transport into the nucleus [ 1 ].

Besides Ntf2, proteins containing this domain include protein kinases, sucrose phosphatases, bacterial ring-hydroxylating dioxygenase beta subunit, protein NXF and many other uncharacterised proteins.

1. Functional analysis of the hydrophobic patch on nuclear transport factor 2 involved in interactions with the nuclear pore in vivo. J. Biol. Chem. 276, 38820-9