InterPro domain: IPR027312

Sda1 is required for 60S pre-ribosomal subunits export to the cytoplasm and may also be required for 60S ribosomal subunit maturation and accumulation. It is involved in G1 events and passage through start, and possibly actin cytoskeleton organisation [ 1 , 2 , 3 ].

1. The Saccharomyces cerevisiae SDA1 gene is required for actin cytoskeleton organization and cell cycle progression. J. Cell. Sci. 113 ( Pt 7), 1199-211
2. The Sda1 protein is required for passage through start. Mol. Biol. Cell 12, 201-19
3. Expression and localization studies of hSDA, the human ortholog of the yeast SDA1 gene. Cell Cycle 3, 486-90