InterPro domain: IPR015883

General Information

  • Identifier IPR015883
  • Description Glycoside hydrolase family 20, catalytic domain
  • Number of genes 392
  • Gene duplication stats Loading...
  • Associated GO terms GO:0005975   GO:0004553  

Abstract

Glycoside hydrolase family 20 ( GH20 ) comprises enzymes with several known activities; beta-hexosaminidase ( 3.2.1.52 ); lacto-N-biosidase ( 3.2.1.140 ); beta-1,6-N-acetylglucosaminidase); and beta-6-SO3-N-acetylglucosaminidase. Carbonyl oxygen of the C-2 acetamido group of the substrate acts as the catalytic nucleophile/base in this family of enzymes [ 1 ].

This entry represents the glycoside hydrolase family 20 catalytic domain. This domain has a TIM barrel fold.


1. Structural-Functional Analysis Reveals a Specific Domain Organization in Family GH20 Hexosaminidases. PLoS One 10, e0128075

Species distribution

Gene table