InterPro domain: IPR013698

General Information

  • Identifier IPR013698
  • Description Squalene epoxidase

Abstract

This domain is found in squalene epoxidase (SE) and related proteins which are found in taxonomically diverse groups of eukaryotes and also in bacteria. SE was first cloned from Saccharomyces cerevisiae (Baker's yeast) where it was named ERG1. It contains a putative FAD binding site and is a key enzyme in the sterol biosynthetic pathway [ 1 ]. Putative transmembrane regions are found to the protein's C terminus.


1. Cloning and expression of squalene epoxidase from the pathogenic yeast Candida albicans. Gene 189, 119-26

Species distribution

Gene table