InterPro domain: IPR012392
General Information
- Identifier IPR012392
- Description Very-long-chain 3-ketoacyl-CoA synthase
- Number of genes 2550
- Gene duplication stats Loading...
- Associated GO terms GO:0016747 GO:0016020 GO:0006633
Abstract
This group represents 3-ketoacyl-CoA synthases (KCSs) from plants [ 1 , 2 ]. They are also known as very long-chain fatty acid (VLCFA) condensing enzymes, and they catalyse the first committed step during the fatty acid elongation process, which is the condensation of C2 units to acyl-CoA. Arabidopsis contains 21 KCS members [ 3 ].
1. CUT1, an Arabidopsis gene required for cuticular wax biosynthesis and pollen fertility, encodes a very-long-chain fatty acid condensing enzyme. Plant Cell 11, 825-38
2. Arabidopsis 3-ketoacyl-coenzyme a synthase9 is involved in the synthesis of tetracosanoic acids as precursors of cuticular waxes, suberins, sphingolipids, and phospholipids. Plant Physiol. 162, 567-80
3. The VLCFA elongase gene family in Arabidopsis thaliana: phylogenetic analysis, 3D modelling and expression profiling. Plant Mol. Biol. 67, 547-66