InterPro domain: IPR012336

General Information

  • Identifier IPR012336
  • Description Thioredoxin-like fold
  • Number of genes 850
  • Gene duplication stats Loading...

Abstract

Several biological processes regulate the activity of target proteins through changes in the redox state of thiol groups (S2 to SH2), where a hydrogen donor is linked to an intermediary disulphide protein. Such processes include the ferredoxin/thioredoxin system, the NADP/thioredoxin system, and the glutathione/glutaredoxin system [ 1 ]. Several of these disulphide proteins share a common structure, consisting of a three-layer alpha/beta/alpha core.


1. Redox regulation: a broadening horizon. null 56, 187-220

Species distribution

Gene table