InterPro domain: IPR009262
General Information
- Identifier IPR009262
- Description Solute carrier family 35 member SLC35F1/F2/F6
- Number of genes 401
- Gene duplication stats Loading...
- Associated GO terms GO:0055085 GO:0022857 GO:0016021
Abstract
This entry contains some of the solute carrier family 35 members, including SLC35F1, SLC35F2 and SLC35F6. In humans, SLC35F6 is involved in the maintenance of mitochondrial membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. It promotes pancreatic ductal adenocarcinoma (PDAC) cell growth and may play a role as a nucleotide-sugar transporter [ 1 ].
1. Identification of C2orf18, termed ANT2BP (ANT2-binding protein), as one of the key molecules involved in pancreatic carcinogenesis. Cancer Sci. 100, 457-64
Species distribution
Gene table
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