InterPro domain: IPR005175

The Plants and Prokaryotes Conserved (PPC) domain contains a hydrophobicregion in the C-terminal, and in the case of plants, is often found in severalproteins with the AT-hook motif. Proteins with PPC domains are found inBacteria, Archaea and the plant kingdom [ 1 , 2 ].

The PPC domain has a single alpha-helix packed against an antiparallel beta-sheet, which is formed by five beta-strands. Three conserved histidine residues appear to form a zinc-binding site, and the domain has been observed to form homotrimers. The domain co-occurs with a thioredoxin-like domain in uncharacterized cyanobacterial proteins [ 3 ].

1. Identification of a novel plant MAR DNA binding protein localized on chromosomal surfaces. Plant Mol. Biol. 56, 225-39
2. Crystal structure of Pyrococcus horikoshii PPC protein at 1.60 A resolution. Proteins 67, 505-7