InterPro domain: IPR004864

This entry represents Pfam LEA_2, or LEA14 (D-95) from Dure. The structure of Arabidopsis LEA14 has been revealed [ 1 ].

LEA (late embryogenesis abundant) proteins were first identified in land plants. Plant LEA proteins have been found to accumulate to high levels during the last stage of seed formation (when a natural desiccation of the seed tissues takes place) and during periods of water deficit in vegetative organs. Later, LEA homologues have also been found in various species [ 2 , 3 ]. They have been classified into several subgroups in Pfam and according to Bray and Dure [ 4 ].

1. Solution structure of a late embryogenesis abundant protein (LEA14) from Arabidopsis thaliana, a cellular stress-related protein. Protein Sci. 14, 2601-9
2. LEA proteins during water stress: not just for plants anymore. Annu. Rev. Physiol. 73, 115-34
3. Highly hydrophilic proteins in prokaryotes and eukaryotes are common during conditions of water deficit. J. Biol. Chem. 275, 5668-74
4. LEA (late embryogenesis abundant) proteins and their encoding genes in Arabidopsis thaliana. BMC Genomics 9, 118