InterPro domain: IPR002119

General Information

  • Identifier IPR002119
  • Description Histone H2A
  • Number of genes 1873
  • Gene duplication stats Loading...
  • Associated GO terms GO:0003677   GO:0000786  

Abstract

Histone H2A is a small, highly conserved nuclear protein that, together with two molecules each of histones H2B, H3 and H4, forms the eukaryotic nucleosome core [ 1 ]; the nucleosome octamer winds ~146 DNA base-pairs. In the mouse, histone H2A can be replaced by histone H2A-like 1 [ 2 ].


1. Phylogenetic analysis of the core histones H2A, H2B, H3, and H4. Nucleic Acids Res. 22, 174-9
2. Pericentric heterochromatin reprogramming by new histone variants during mouse spermiogenesis. J. Cell Biol. 176, 283-94

Species distribution

Gene table