Gene: Sopen12g002310

General Information

Description Encodes a proton antiporter. Involved in the transportation of proanthocyanidin precursors into the vacuole. In vitro transport experiments showed that cyanidin-3-O-glucoside (anthocyanin) was an effective substrate, whereas the proanthocyanidin precursor epicatechin was not transported. However catechin-3-O-glucoside inhibited anthocyanin transport in a dose-dependent manner suggesting that glycosylated epicatechin is the in vivo substrate. Recessive mutation has strong reduction of proanthocyanidin deposition in vacuoles and has reduced dormancy. Expressed in the endothelium of ovules and developing seeds. | TRANSPARENT TESTA 12 (TT12) | CONTAINS InterPro DOMAIN/s: Multi antimicrobial extrusion protein MatE | BEST Arabidopsis thaliana protein match is: MATE efflux family protein

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:1990961	IEA	InterPro	xenobiotic detoxification by transmembrane export across the plasma membrane
GO:0055085	IEA	InterPro	transmembrane transport
GO:0010231	ISO	PLAZA Integrative Orthology	maintenance of seed dormancy	AT3G59030
GO:0010023	ISO	PLAZA Integrative Orthology	proanthocyanidin biosynthetic process	AT3G59030

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0042910	IEA	InterPro	xenobiotic transmembrane transporter activity
GO:0015297	IEA	InterPro	antiporter activity
GO:0015299	ISO	PLAZA Integrative Orthology	solute:proton antiporter activity	AT3G59030

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0016020	IEA	InterPro	membrane
GO:0009705	ISO	PLAZA Integrative Orthology	plant-type vacuole membrane	AT3G59030

Experimental Evidence

Computational Reviewed Evidence

Electronic Evidence

InterPro	Description
IPR045069	Multidrug and toxic compound extrusion family, eukaryotic
IPR002528	Multi antimicrobial extrusion protein

Mapman id	Description
24.2.4.1.1	Solute transport.carrier-mediated transport.MOP superfamily.MATE family.metabolite transporter (DTX)