Gene: Sopen11g005390
General Information
Structural Information
- Species Solanum pennellii
- Gene Identifier Sopen11g005390
- Transcript Identifier Sopen11g005390.1
- Gene Type Coding gene
- Location Spenn-ch11 : 3776440-3780192 : negative
Gene Family Information
- ID HOM05D004350
- #Genes/#Species 164/96
- Phylogenetic origin
- ID ORTHO05D005260
- #Genes/#Species 161/96
- Phylogenetic origin
Gene Duplication Information
- Block Duplication Block duplicate
Labels
Identifiers
- tid Sopen11g005390.1
Descriptions
- Description Protein tyrosine phosphatase-like involved in cell division and differentiation. Interacts with CDKA, 1 only in its phosphorylated form, preventing dephosphorylation. Overexpression slowed down cell division in suspension cell cultures at the G2-to-M transition and early mitosis and inhibited Arabidopsis seedling growth. Localized in the cytoplasm of dividing cells but moved into the nucleus upon cell differentiation. Based on complementation of yeast mutant PAS2 has acyl-CoA dehydratase activity. It interacts with CER10, a component of the microsomal fatty acid elongase complex, suggesting a role in synthesis of VLCFAs (very long chain fatty acids). | PASTICCINO 2 (PAS2) | CONTAINS InterPro DOMAIN/s: Protein-tyrosine phosphatase-like, PTPLA | BEST Arabidopsis thaliana protein match is: Protein-tyrosine phosphatase-like, PTPLA ., Protein-tyrosine phosphatase-like, PTPLA
- Loading (ortholog descriptions from ath)...
Functional Annotation
Biological Process
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0051302 | ISO | PLAZA Integrative Orthology | regulation of cell division | AT5G10480 |
| GO:0048640 | ISO | PLAZA Integrative Orthology | negative regulation of developmental growth | AT5G10480 |
| GO:0030154 | ISO | PLAZA Integrative Orthology | cell differentiation | AT5G10480 |
| GO:0042761 | ISO | PLAZA Integrative Orthology | very long-chain fatty acid biosynthetic process | AT5G10480 |
| GO:0050732 | ISO | PLAZA Integrative Orthology | negative regulation of peptidyl-tyrosine phosphorylation | AT5G10480 |
Molecular Function
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0005515 | ISO | PLAZA Integrative Orthology | protein binding | AT5G10480 |
| GO:0080023 | ISO | PLAZA Integrative Orthology | 3R-hydroxyacyl-CoA dehydratase activity | AT5G10480 |
Cellular Component
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0005634 | ISO | PLAZA Integrative Orthology | nucleus | AT5G10480 |
| GO:0016021 | ISO | PLAZA Integrative Orthology | integral component of membrane | AT5G10480 |
| GO:0005829 | ISO | PLAZA Integrative Orthology | cytosol | AT5G10480 |
| GO:0009923 | ISO | PLAZA Integrative Orthology | fatty acid elongase complex | AT5G10480 |
Color Legend
| Experimental Evidence |
| Computational Reviewed Evidence |
| Electronic Evidence |
| InterPro | Description |
|---|---|
| IPR007482 | Protein-tyrosine phosphatase-like, PTPLA |
| Mapman id | Description |
|---|---|
| 5.1.6.1.2 | Lipid metabolism.fatty acid biosynthesis.endoplasmic reticulum-localized fatty acid elongase (FAE) system.fatty acid elongation complex.3-hydroxyacyl-CoA dehydratase (HCD) |