Gene: Sopen06g035820

General Information

Description Probable histone H2AXb - Oryza sativa (Rice), Encodes HTA5, a histone H2A protein. H2AX is a meiosis-specific isoform of histone H2A. Upon DSB formation, rapid accumulation of phosphorylated H2AX (, #947, -H2AX) occurs around the break site. H2AX foci accumulate in early G2. Immunolocalization studies in spread preparations of wild-type meiocytes at G2/early leptotene revealed the accumulation of numerous rather diffuse, #947, -H2AX foci throughout the chromatin. However, their accumulation is not contemporaneous with that of AtSPO11-1. At 3 h post-S, no, #947, -H2AX foci are detected. During the 3- to 5-h window when AtSPO11-1 foci rapidly disappear, there is an equally swift accumulation of, #947, -H2AX to a maximum of 50 diffuse foci. The level of, #947, H2AX then remains constant for a further 13 h before undergoing a gradual decrease to 10Ã±20 foci in the 18- to 24-h post-S period. By 30 h the foci have disappeared from the chromatin. | H2AXA | FUNCTIONS IN: DNA binding | INVOLVED IN: nucleosome assembly | LOCATED IN: nucleus | EXPRESSED IN: 23 plant structures | EXPRESSED DURING: 13 growth stages | CONTAINS InterPro DOMAIN/s: Histone H2A , Histone-fold , Histone core | BEST Arabidopsis thaliana protein match is: gamma histone variant H2AX

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0003677	IEA	InterPro	DNA binding
GO:0046982	IEA	InterPro	protein heterodimerization activity

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0000786	IEA	InterPro	nucleosome

Experimental Evidence

Computational Reviewed Evidence

Electronic Evidence

Mapman id	Description
12.1.1.1	Chromatin organisation.chromatin structure.DNA wrapping.histone (H2A)