Gene: Sopen05g006410
General Information
Structural Information
- Species Solanum pennellii
- Gene Identifier Sopen05g006410
- Transcript Identifier Sopen05g006410.1
- Gene Type Coding gene
- Location Spenn-ch05 : 5410144-5413040 : negative
Gene Family Information
- ID HOM05D002721
- #Genes/#Species 253/91
- Phylogenetic origin
- ID ORTHO05D002919
- #Genes/#Species 254/91
- Phylogenetic origin
Gene Duplication Information
Labels
Identifiers
- tid Sopen05g006410.1
Descriptions
- Description Encodes one of the WPP domain-interacting proteins (WIT1/AT5G11390, WIT2/AT1G68910) required for RanGAP nuclear envelope association in root tip cells. Ran GTPase plays essential roles in multiple cellular processes, including nucleocytoplasmic transport, spindle formation, and postmitotic nuclear envelope reassembly. The cytoplasmic Ran GTPase activating protein RanGAP is critical to establish a functional RanGTP/RanGDP gradient across the nuclear envelope and is associated with the outer surface of the nuclear envelope in metazoan and higher plant cells. Arabidopsis thaliana RanGAP association with the root tip nuclear envelope requires a family of likely plant-specific nucleoporins combining coiled-coil and transmembrane domains (CC-TMD) and WPP domain-interacting proteins (WIPs). WIT1 and WIT2 have been identified as a second family of CC-TMD proteins, structurally similar, yet clearly distinct from the WIP family, that is required for RanGAP nuclear envelop association in root tip cells. | WPP domain-interacting protein 2 (WIT2) | FUNCTIONS IN: molecular_function unknown | INVOLVED IN: biological_process unknown | LOCATED IN: cellular_component unknown | EXPRESSED IN: 22 plant structures | EXPRESSED DURING: 13 growth stages | BEST Arabidopsis thaliana protein match is: WPP domain-interacting protein 1 .
- Loading (ortholog descriptions from ath)...
Functional Annotation
Biological Process
GO term | Evidence(s) | Provider(s) | Description | Source(s) |
---|---|---|---|---|
GO:2000769 | ISO | PLAZA Integrative Orthology | regulation of establishment or maintenance of cell polarity regulating cell shape | AT1G68910 |
Molecular Function
GO term | Evidence(s) | Provider(s) | Description | Source(s) |
---|---|---|---|---|
GO:0005515 | ISO | PLAZA Integrative Orthology | protein binding | AT1G68910 |
GO:0080115 | ISO | PLAZA Integrative Orthology | myosin XI tail binding | AT1G68910 |
Color Legend
Experimental Evidence |
Computational Reviewed Evidence |
Electronic Evidence |
InterPro | Description |
---|---|
IPR039976 | WPP domain-interacting tail-anchored protein |
Mapman id | Description |
---|---|
20.4.2.2 | Cytoskeleton organisation.nuclear dynamics.nuclear movement.myosin-SUN-WIP adaptor (WIT) |