Gene: Sopen03g008440
General Information
Structural Information
- Species Solanum pennellii
- Gene Identifier Sopen03g008440
- Transcript Identifier Sopen03g008440.1
- Gene Type Coding gene
- Location Spenn-ch03 : 8496866-8498845 : negative
Gene Family Information
- ID HOM05D002723
- #Genes/#Species 253/97
- Phylogenetic origin
- ID ORTHO05D003240
- #Genes/#Species 236/97
- Phylogenetic origin
Gene Duplication Information
Labels
Identifiers
- tid Sopen03g008440.1
Descriptions
- Description Acetolactate synthase 2, chloroplast precursor (EC 2.2.1.6) (Acetolactate synthase II) (Acetohydroxy-acid synthase II) (ALS II) - Nicotiana tabacum (Common tobacco), Catalyzes the formation of acetolactate from pyruvate, the first step in valine and isoleucine biosynthesis. Requires FAD, thiamine pyrophosphate and Mg. Inhibited by the sulphonylurea herbicide, chlorsulphuron, and the imidazolinone herbicide, imazapyr. The obtained crystal structure of acetohydroxyacid synthase AHAS, EC 2.2.1.6)in complex with herbicides of the sulphonylurea and imidazolinone family reveals the molecular basis for substrate/inhibitor binding. | chlorsulfuron/imidazolinone resistant 1 (CSR1) | FUNCTIONS IN: acetolactate synthase activity, pyruvate decarboxylase activity | INVOLVED IN: branched chain family amino acid biosynthetic process | LOCATED IN: chloroplast | EXPRESSED IN: 24 plant structures | EXPRESSED DURING: 15 growth stages | CONTAINS InterPro DOMAIN/s: TPP-binding enzyme, conserved site , Thiamine pyrophosphate enzyme, central domain , Acetolactate synthase, large subunit, biosynthetic , Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain , Thiamine pyrophosphate enzyme, C-terminal TPP-binding | BEST Arabidopsis thaliana protein match is: Thiamine pyrophosphate dependent pyruvate decarboxylase family protein
- Loading (ortholog descriptions from ath)...
Functional Annotation
Biological Process
GO term | Evidence(s) | Provider(s) | Description | Source(s) |
---|---|---|---|---|
GO:0009082 | IEA | InterPro | branched-chain amino acid biosynthetic process | |
GO:0009099 | ISO | PLAZA Integrative Orthology | valine biosynthetic process | AT3G48560 |
Molecular Function
GO term | Evidence(s) | Provider(s) | Description | Source(s) |
---|---|---|---|---|
GO:0000287 | IEA | InterPro | magnesium ion binding | |
GO:0003984 | IEA | InterPro | acetolactate synthase activity | |
GO:0030976 | IEA | InterPro | thiamine pyrophosphate binding | |
GO:0050660 | IEA | InterPro | flavin adenine dinucleotide binding | |
GO:0003824 | IEA | InterPro | catalytic activity | |
GO:0005515 | ISO | PLAZA Integrative Orthology | protein binding | AT3G48560 |
GO:0004737 | ISO | PLAZA Integrative Orthology | pyruvate decarboxylase activity | AT3G48560 |
Cellular Component
GO term | Evidence(s) | Provider(s) | Description | Source(s) |
---|---|---|---|---|
GO:0009570 | ISO | PLAZA Integrative Orthology | chloroplast stroma | AT3G48560 |
GO:0009507 | ISO | PLAZA Integrative Orthology | chloroplast | AT3G48560 |
Color Legend
Experimental Evidence |
Computational Reviewed Evidence |
Electronic Evidence |
InterPro | Description |
---|---|
IPR029035 | DHS-like NAD/FAD-binding domain superfamily |
IPR012846 | Acetolactate synthase, large subunit, biosynthetic |
IPR029061 | Thiamin diphosphate-binding fold |
IPR012001 | Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain |
IPR012000 | Thiamine pyrophosphate enzyme, central domain |
IPR011766 | Thiamine pyrophosphate enzyme, C-terminal TPP-binding |
IPR039368 | Acetolactate synthase large subunit, TPP binding domain |
Mapman id | Description |
---|---|
4.1.2.2.8.3.1 | Amino acid metabolism.biosynthesis.aspartate family.aspartate-derived amino acids.isoleucine.acetolactate synthase complex.catalytic subunit |
4.1.3.2.1.1 | Amino acid metabolism.biosynthesis.pyruvate family.pyruvate-derived amino acids.acetolactate synthase complex.catalytic subunit |