Gene: Sopen02g026920
General Information
Structural Information
- Species Solanum pennellii
- Gene Identifier Sopen02g026920
- Transcript Identifier Sopen02g026920.1
- Gene Type Coding gene
- Location Spenn-ch02 : 49731794-49734522 : negative
Gene Family Information
- ID HOM05D000935
- #Genes/#Species 645/97
- Phylogenetic origin
- ID ORTHO05D001483
- #Genes/#Species 400/97
- Phylogenetic origin
Gene Duplication Information
- Block Duplication Block duplicate
Labels
Identifiers
- tid Sopen02g026920.1
Descriptions
- Description 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 (EC 1.1.1.34) (HMG-CoA reductase 1) (HMGR1) (HMGR) - Solanum tuberosum (Potato), Encodes a 3-hydroxy-3-methylglutaryl coenzyme A reductase, which is involved in melavonate biosynthesis and performs the first committed step in isoprenoid biosynthesis. Expression is activated in dark in leaf tissue but not controlled by light in the root (confine | hydroxy methylglutaryl CoA reductase 1 (HMG1) | CONTAINS InterPro DOMAIN/s: Hydroxymethylglutaryl-CoA reductase, class I, catalytic , Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding , Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding , Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic | BEST Arabidopsis thaliana protein match is: 3-hydroxy-3-methylglutaryl-CoA reductase 2
- Loading (ortholog descriptions from ath)...
Functional Annotation
Biological Process
GO term | Evidence(s) | Provider(s) | Description | Source(s) |
---|---|---|---|---|
GO:0008299 | IEA | InterPro | isoprenoid biosynthetic process | |
GO:0015936 | IEA | InterPro | coenzyme A metabolic process | |
GO:0019287 | ISO | PLAZA Integrative Orthology | isopentenyl diphosphate biosynthetic process, mevalonate pathway | AT1G76490 |
GO:0016104 | ISO | PLAZA Integrative Orthology | triterpenoid biosynthetic process | AT2G17370 |
GO:0016126 | ISO | PLAZA Integrative Orthology | sterol biosynthetic process | AT2G17370 |
Molecular Function
GO term | Evidence(s) | Provider(s) | Description | Source(s) |
---|---|---|---|---|
GO:0004420 | IEA | InterPro | hydroxymethylglutaryl-CoA reductase (NADPH) activity | |
GO:0005515 | IEA | InterPro | protein binding | |
GO:0016616 | IEA | InterPro | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
Cellular Component
GO term | Evidence(s) | Provider(s) | Description | Source(s) |
---|---|---|---|---|
GO:0005789 | ISO | PLAZA Integrative Orthology | endoplasmic reticulum membrane | AT1G76490 |
GO:0005777 | ISO | PLAZA Integrative Orthology | peroxisome | AT1G76490 |
GO:0043231 | ISO | PLAZA Integrative Orthology | intracellular membrane-bounded organelle | AT2G17370 |
GO:0016020 | ISO | PLAZA Integrative Orthology | membrane | AT1G76490 |
GO:0005783 | ISO | PLAZA Integrative Orthology | endoplasmic reticulum | AT1G76490 |
GO:0009536 | ISO | PLAZA Integrative Orthology | plastid | AT1G76490 |
Color Legend
Experimental Evidence |
Computational Reviewed Evidence |
Electronic Evidence |
InterPro | Description |
---|---|
IPR004554 | Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type |
IPR002202 | Hydroxymethylglutaryl-CoA reductase, class I/II |
IPR009023 | Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily |
IPR023074 | Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily |
IPR023282 | Hydroxymethylglutaryl-CoA reductase, N-terminal |
IPR009029 | Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily |
Mapman id | Description |
---|---|
9.1.1.3 | Secondary metabolism.terpenoids.mevalonate pathway.3-hydroxy-3-methylglutaryl-CoA reductase |