Gene: AT5G63920

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT5G63920
  • Transcript Identifier AT5G63920.1
  • Gene Type Coding gene
  • Location Chr5 : 25574533-25581230 : positive

Gene Family Information

  • ID HOM05D002182
  • #Genes/#Species 307/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT5G63920.1
  • symbol TOP3A
  • Alias AtTOP3alpha
  • uniprot Q9LVP1

Descriptions

  • Description topoisomerase 3alpha
  • Computational description topoisomerase 3alpha (TOP3A); FUNCTIONS IN: DNA topoisomerase activity, DNA topoisomerase type I activity, DNA binding, zinc ion binding, nucleic acid binding; INVOLVED IN: in 7 processes; LOCATED IN: chromosome; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA topoisomerase, type IA, zn finger (InterPro:IPR013498), DNA topoisomerase, type IA, core (InterPro:IPR000380), DNA topoisomerase, type IA, domain 2 (InterPro:IPR003601), DNA topoisomerase, type IA, DNA-binding (InterPro:IPR003602), DNA topoisomerase, type IA, central (InterPro:IPR013497), Zinc finger, GRF-type (InterPro:IPR010666), DNA topoisomerase, type IA, central region, subdomain 3 (InterPro:IPR013826), Toprim domain, subgroup (InterPro:IPR006154), DNA topoisomerase, type IA, central region, subdomain 1 (InterPro:IPR013824), Toprim domain (InterPro:IPR006171), Zinc finger, CCHC-type (InterPro:IPR001878); BEST Arabidopsis thaliana protein match is: DNA topoisomerase, type IA, core (TAIR:AT2G32000.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006265
IEA
GOA DatabaseDNA topological change
GO:0006265
IBA
Gene OntologyDNA topological change1
GO:0006265
IEA
InterProDNA topological change
GO:0051321
IEA
GOA Databasemeiotic cell cycle
GO:0051321
IMP
Gene Ontologymeiotic cell cycle2
GO:0007059
IMP
Gene Ontologychromosome segregation2
GO:0006281
IMP
Gene OntologyDNA repair2
GO:0000712
IMP
Gene Ontologyresolution of meiotic recombination intermediates2
GO:0000278
IMP
Gene Ontologymitotic cell cycle2

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003916
IEA
GOA DatabaseDNA topoisomerase activity
GO:0003916
IBA
Gene OntologyDNA topoisomerase activity1
GO:0003916
IEA
InterProDNA topoisomerase activity
GO:0003676
IEA
GOA Databasenucleic acid binding
GO:0003676
IEA
InterPronucleic acid binding
GO:0008270
IEA
Gene Ontologyzinc ion binding
GO:0008270
IEA
InterProzinc ion binding
GO:0003917
IEA
Gene OntologyDNA topoisomerase type I (single strand cut, ATP-independent) activity
GO:0003917
IEA
InterProDNA topoisomerase type I (single strand cut, ATP-independent) activity
GO:0003677
IEA
GOA DatabaseDNA binding
GO:0003677
IEA
InterProDNA binding
GO:0016853
IEA
GOA Databaseisomerase activity
GO:0046872
IEA
GOA Databasemetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005694
IEA
Gene Ontologychromosome
GO:0005694
IEA
InterProchromosome
GO:0005634
ISM, IBA
Gene Ontologynucleus1

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR013498 DNA topoisomerase, type IA, zn finger
IPR013824 DNA topoisomerase, type IA, central region, subdomain 1
IPR000380 DNA topoisomerase, type IA
IPR013825 DNA topoisomerase, type IA, central region, subdomain 2
IPR013497 DNA topoisomerase, type IA, central
IPR023405 DNA topoisomerase, type IA, core domain
IPR034144 DNA topoisomerase 3-like, TOPRIM domain
IPR006171 TOPRIM domain
IPR010666 Zinc finger, GRF-type
IPR003602 DNA topoisomerase, type IA, DNA-binding domain
IPR013826 DNA topoisomerase, type IA, central region, subdomain 3
IPR036875 Zinc finger, CCHC-type superfamily
IPR003601 DNA topoisomerase, type IA, domain 2
IPR001878 Zinc finger, CCHC-type
Mapman id Description
13.3.5.5.3.2 Cell cycle organisation.mitosis and meiosis.meiotic recombination.meiotic crossover.RTR Holliday junction dissolution complex.topoisomerase component TOP3-alpha