Gene: AT5G43940
General Information
Structural Information
- Species Arabidopsis thaliana
- Gene Identifier AT5G43940
- Transcript Identifier AT5G43940.2
- Gene Type Coding gene
- Location Chr5 : 17684265-17686379 : positive
Gene Family Information
- ID HOM05D000219
- #Genes/#Species 1864/100
- Phylogenetic origin
- ID ORTHO05D000226
- #Genes/#Species 1343/100
- Phylogenetic origin
Gene Duplication Information
Labels
Identifiers
- tid AT5G43940.2
- symbol HOT5
- Alias ADH2,ALCOHOL DEHYDROGENASE 2,ATGSNOR1,GSNOR,S-NITROSOGLUTATHIONE REDUCTASE,PAR2,PARAQUAT RESISTANT 2
- full_name sensitive to hot temperatures 5
- uniprot Q96533
Descriptions
- Description GroES-like zinc-binding dehydrogenase family protein
- Computational description sensitive to hot temperatures 5 (HOT5); FUNCTIONS IN: S-(hydroxymethyl)glutathione dehydrogenase activity, S-nitrosoglutathione reductase activity; INVOLVED IN: in 6 processes; LOCATED IN: peroxisome; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: GroES-like (InterPro:IPR011032), Alcohol dehydrogenase GroES-like (InterPro:IPR013154), Alcohol dehydrogenase, zinc-containing, conserved site (InterPro:IPR002328), Alcohol dehydrogenase, C-terminal (InterPro:IPR013149), Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase (InterPro:IPR014183), Alcohol dehydrogenase superfamily, zinc-containing (InterPro:IPR002085); BEST Arabidopsis thaliana protein match is: alcohol dehydrogenase 1 (TAIR:AT1G77120.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
- Computational description sensitive to hot temperatures 5 (HOT5); CONTAINS InterPro DOMAIN/s: GroES-like (InterPro:IPR011032), Alcohol dehydrogenase, zinc-containing, conserved site (InterPro:IPR002328), Alcohol dehydrogenase GroES-like (InterPro:IPR013154), Alcohol dehydrogenase, C-terminal (InterPro:IPR013149), Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase (InterPro:IPR014183), Alcohol dehydrogenase superfamily, zinc-containing (InterPro:IPR002085); BEST Arabidopsis thaliana protein match is: alcohol dehydrogenase 1 (TAIR:AT1G77120.1).
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Functional Annotation
Biological Process
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0046292 | IDA, IGI | Gene Ontology | formaldehyde metabolic process | 1 2 |
| GO:0006069 | IEA | Gene Ontology | ethanol oxidation | |
| GO:0006069 | IEA | InterPro | ethanol oxidation | |
| GO:0046294 | IBA | GOA Database | formaldehyde catabolic process | |
| GO:0008219 | IMP | Gene Ontology | cell death | 3 |
| GO:0048316 | IMP | Gene Ontology | seed development | 4 |
| GO:0010286 | IMP | Gene Ontology | heat acclimation | 4 |
Molecular Function
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0051903 | IBA IEA | GOA Database | S-(hydroxymethyl)glutathione dehydrogenase activity | |
| GO:0051903 | IDA | Gene Ontology | S-(hydroxymethyl)glutathione dehydrogenase activity | 2 |
| GO:0051903 | IEA | InterPro | S-(hydroxymethyl)glutathione dehydrogenase activity | |
| GO:0008270 | IBA | GOA Database | zinc ion binding | |
| GO:0008270 | IEA | Gene Ontology | zinc ion binding | |
| GO:0008270 | IEA | InterPro | zinc ion binding | |
| GO:0004024 | IBA | GOA Database | alcohol dehydrogenase activity, zinc-dependent | |
| GO:0016491 | IEA | GOA Database | oxidoreductase activity | |
| GO:0046872 | IEA | GOA Database | metal ion binding | |
| GO:0018455 | IEA | GOA Database | alcohol dehydrogenase [NAD(P)+] activity | |
| GO:0004022 | IEA | GOA Database | alcohol dehydrogenase (NAD+) activity | |
| GO:0080007 | IMP | Gene Ontology | S-nitrosoglutathione reductase activity | 4 |
| GO:0106322 | IEA | Gene Ontology | S-(hydroxymethyl)glutathione dehydrogenase NAD activity | |
| GO:0106321 | IEA | Gene Ontology | S-(hydroxymethyl)glutathione dehydrogenase NADP activity |
Cellular Component
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0005829 | IBA | GOA Database | cytosol | |
| GO:0005829 | HDA | Gene Ontology | cytosol | 5 |
| GO:0005737 | IEA | GOA Database | cytoplasm | |
| GO:0005737 | ISM | Gene Ontology | cytoplasm | |
| GO:0009536 | HDA | Gene Ontology | plastid | 6 |
| GO:0005777 | HDA | Gene Ontology | peroxisome | 7 |
Color Legend
| Experimental Evidence |
| Computational Reviewed Evidence |
| Electronic Evidence |
| Mapman id | Description |
|---|---|
| 18.7.1 | Protein modification.S-nitrosylation.S-nitrosoglutathione reductase (GSNOR) |