Gene: AT5G41370
General Information
Structural Information
- Species Arabidopsis thaliana
- Gene Identifier AT5G41370
- Transcript Identifier AT5G41370.1
- Gene Type Coding gene
- Location Chr5 : 16551337-16555792 : positive
Gene Family Information
- ID HOM05D003441
- #Genes/#Species 198/99
- Phylogenetic origin
- ID ORTHO05D004516
- #Genes/#Species 178/99
- Phylogenetic origin
Gene Duplication Information
- Tandem Duplication Tandem duplicate
Labels
Identifiers
- tid AT5G41370.1
- symbol XPB1
- Alias ATXPB1,ARABIDOPSIS HOMOLOG OF XERODERMA PIGMENTOSUM COMPLEMENTATION GROUP B 1
- full_name homolog of xeroderma pigmentosum complementation group B 1
- uniprot Q38861
Descriptions
- Description DNA repair helicase XPB1-like protein
- Computational description homolog of xeroderma pigmentosum complementation group B 1 (XPB1); FUNCTIONS IN: in 7 functions; INVOLVED IN: response to UV, response to toxin; LOCATED IN: nucleus, cytoplasm; EXPRESSED IN: whole plant, male gametophyte, pollen tube; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, seedling growth; CONTAINS InterPro DOMAIN/s: Restriction endonuclease, type I, R subunit/Type III, Res subunit (InterPro:IPR006935), DEAD-like helicase, N-terminal (InterPro:IPR014001), Xeroderma pigmentosum group B protein (XP-B) (InterPro:IPR001161), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: homolog of Xeroderma pigmentosum complementation group B 2 (TAIR:AT5G41360.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
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Functional Annotation
Biological Process
GO term | Evidence(s) | Provider(s) | Description | Source(s) |
---|---|---|---|---|
GO:0006367 | IEA | GOA Database | transcription initiation from RNA polymerase II promoter | |
GO:0006367 | IBA | Gene Ontology | transcription initiation from RNA polymerase II promoter | 1 |
GO:0006367 | IEA | InterPro | transcription initiation from RNA polymerase II promoter | |
GO:0006289 | IEA | GOA Database | nucleotide-excision repair | |
GO:0006289 | IEA | InterPro | nucleotide-excision repair | |
GO:0006974 | IEA | GOA Database | cellular response to DNA damage stimulus | |
GO:0006281 | IEA | GOA Database | DNA repair | |
GO:0032508 | IEA | GOA Database | DNA duplex unwinding | |
GO:0033683 | IBA | Gene Ontology | nucleotide-excision repair, DNA incision | 1 |
GO:0009411 | IEP | Gene Ontology | response to UV | 2 |
GO:0009636 | IMP | Gene Ontology | response to toxic substance |
Molecular Function
GO term | Evidence(s) | Provider(s) | Description | Source(s) |
---|---|---|---|---|
GO:0003678 | IEA | GOA Database | DNA helicase activity | |
GO:0003678 | IEA | InterPro | DNA helicase activity | |
GO:0016787 | IEA | GOA Database | hydrolase activity | |
GO:0016787 | IEA | InterPro | hydrolase activity | |
GO:0005524 | IEA | GOA Database | ATP binding | |
GO:0005524 | IEA | InterPro | ATP binding | |
GO:0003677 | IEA | GOA Database | DNA binding | |
GO:0003677 | IEA | InterPro | DNA binding | |
GO:0004386 | IEA | GOA Database | helicase activity | |
GO:0000166 | IEA | GOA Database | nucleotide binding | |
GO:0043138 | IBA | Gene Ontology | 3'-5' DNA helicase activity | 1 |
Cellular Component
GO term | Evidence(s) | Provider(s) | Description | Source(s) |
---|---|---|---|---|
GO:0005634 | IDA IEA | GOA Database | nucleus | |
GO:0005634 | HDA ISM | Gene Ontology | nucleus | 3 |
GO:0005737 | IDA | GOA Database | cytoplasm | |
GO:0005737 | HDA | Gene Ontology | cytoplasm | 3 |
GO:0005675 | IBA | Gene Ontology | transcription factor TFIIH holo complex | 1 |
GO:0000112 | IBA | Gene Ontology | nucleotide-excision repair factor 3 complex | 1 |
GO:0097550 | IBA | Gene Ontology | transcription preinitiation complex | 1 |
Color Legend
Experimental Evidence |
Computational Reviewed Evidence |
Electronic Evidence |
InterPro | Description |
---|---|
IPR032438 | ERCC3/RAD25/XPB helicase, C-terminal domain |
IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
IPR032830 | Helicase XPB/Ssl2, N-terminal domain |
IPR006935 | Helicase/UvrB, N-terminal |
IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
IPR001650 | Helicase, C-terminal |
IPR001161 | Helicase XPB/Ssl2 |
Mapman id | Description |
---|---|
14.6.3.2.3 | DNA damage response.nucleotide excision repair (NER).multi-functional TFIIh complex.core module.subunit SSL2/XPB |
15.3.3.5.1.3 | RNA biosynthesis.RNA polymerase II-dependent transcription.transcription initiation.TFIIh basal transcription factor complex.core module.component SSL2/XPB |