Gene: AT5G27380
General Information
Structural Information
- Species Arabidopsis thaliana
- Gene Identifier AT5G27380
- Transcript Identifier AT5G27380.1
- Gene Type Coding gene
- Location Chr5 : 9668211-9670912 : negative
Gene Family Information
- ID HOM05D003767
- #Genes/#Species 183/97
- Phylogenetic origin
- ID ORTHO05D004507
- #Genes/#Species 178/96
- Phylogenetic origin
Gene Duplication Information
Labels
Identifiers
- tid AT5G27380.1
- symbol GSH2
- Alias AtGSH2,GSHB
- uniprot P46416
Descriptions
- Description glutathione synthetase 2
- Computational description glutathione synthetase 2 (GSH2); FUNCTIONS IN: glutathione synthase activity; INVOLVED IN: response to jasmonic acid stimulus, N-terminal protein myristoylation, glutathione biosynthetic process; LOCATED IN: cytosol, chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: PreATP-grasp-like fold (InterPro:IPR016185), ATP-grasp fold, subdomain 2 (InterPro:IPR013816), Glutathione synthase, eukaryotic (InterPro:IPR005615), Glutathione synthase, substrate-binding, eukaryotic (InterPro:IPR004887), Glutathione synthase, alpha-helical, eukaryotic (InterPro:IPR014042); Has 644 Blast hits to 607 proteins in 239 species: Archae - 0; Bacteria - 51; Metazoa - 212; Fungi - 156; Plants - 112; Viruses - 0; Other Eukaryotes - 113 (source: NCBI BLink).
- Loading (ortholog descriptions from ath)...
Functional Annotation
Biological Process
GO term | Evidence(s) | Provider(s) | Description | Source(s) |
---|---|---|---|---|
GO:0006750 | IDA, IGI IEA | Gene Ontology | glutathione biosynthetic process | 1 2 |
GO:0006750 | IEA | InterPro | glutathione biosynthetic process | |
GO:0006979 | ISO | PLAZA Integrative Orthology | response to oxidative stress | Zm00001eb137820 |
GO:0009635 | ISO | PLAZA Integrative Orthology | response to herbicide | Zm00001eb137820 |
GO:0006950 | IEP | Gene Ontology | response to stress | 3 |
GO:0009753 | IEP | Gene Ontology | response to jasmonic acid | 4 |
Molecular Function
GO term | Evidence(s) | Provider(s) | Description | Source(s) |
---|---|---|---|---|
GO:0000166 | IEA | GOA Database | nucleotide binding | |
GO:0043295 | ISS, IBA | Gene Ontology | glutathione binding | 5 |
GO:0004363 | IEA | GOA Database | glutathione synthase activity | |
GO:0004363 | IDA, IGI IBA | Gene Ontology | glutathione synthase activity | 2 5 6 |
GO:0004363 | IEA | InterPro | glutathione synthase activity | |
GO:0046872 | IEA | GOA Database | metal ion binding | |
GO:0016874 | IEA | GOA Database | ligase activity | |
GO:0016874 | IEA | InterPro | ligase activity | |
GO:0005524 | IEA | GOA Database | ATP binding | |
GO:0005524 | ISS | Gene Ontology | ATP binding | |
GO:0005524 | IEA | InterPro | ATP binding | |
GO:0000287 | ISS | Gene Ontology | magnesium ion binding | |
GO:0042803 | ISS | Gene Ontology | protein homodimerization activity |
Cellular Component
GO term | Evidence(s) | Provider(s) | Description | Source(s) |
---|---|---|---|---|
GO:0005829 | IDA IBA TAS | Gene Ontology | cytosol | 5 7 8 |
GO:0009507 | IEA | GOA Database | chloroplast | |
GO:0009507 | IDA, HDA ISM | Gene Ontology | chloroplast | 8 9 |
GO:0009536 | IEA | GOA Database | plastid | |
GO:0009536 | HDA | Gene Ontology | plastid | 10 |
Color Legend
Experimental Evidence |
Computational Reviewed Evidence |
Electronic Evidence |
InterPro | Description |
---|---|
IPR005615 | Glutathione synthase |
IPR037013 | Glutathione synthase, substrate-binding domain superfamily |
IPR004887 | Glutathione synthase, substrate-binding domain |
IPR014709 | Glutathione synthase, C-terminal, eukaryotic |
IPR014042 | Glutathione synthase, alpha-helical |
IPR014049 | Glutathione synthase, N-terminal, eukaryotic |
IPR016185 | Pre-ATP-grasp domain superfamily |
Mapman id | Description |
---|---|
10.3.1.2 | Redox homeostasis.glutathione-based redox regulation.glutathione biosynthesis.glutathione synthetase (GS) |