Gene: AT5G14590

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT5G14590
  • Transcript Identifier AT5G14590.1
  • Gene Type Coding gene
  • Location Chr5 : 4703533-4706627 : negative

Gene Family Information

  • ID HOM05D001485
  • #Genes/#Species 428/99
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT5G14590.1
  • uniprot Q8LPJ5

Descriptions

  • Description Isocitrate/isopropylmalate dehydrogenase family protein
  • Computational description Isocitrate/isopropylmalate dehydrogenase family protein; FUNCTIONS IN: NAD or NADH binding, isocitrate dehydrogenase (NADP ) activity, magnesium ion binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; INVOLVED IN: oxidation reduction, isocitrate metabolic process, metabolic process; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Isocitrate/isopropylmalate dehydrogenase (InterPro:IPR001804), Isocitrate dehydrogenase NADP-dependent, eukaryotic (InterPro:IPR004790), Isocitrate/isopropylmalate dehydrogenase, conserved site (InterPro:IPR019818); BEST Arabidopsis thaliana protein match is: cytosolic NADP -dependent isocitrate dehydrogenase (TAIR:AT1G65930.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006102
IEA
GOA Databaseisocitrate metabolic process
GO:0006102
IBA
Gene Ontologyisocitrate metabolic process1
GO:0006102
IEA
InterProisocitrate metabolic process
GO:0006099
IEA
GOA Databasetricarboxylic acid cycle
GO:0006739
IBA
Gene OntologyNADP metabolic process1

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016616
IEA
GOA Databaseoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0016616
IEA
InterProoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0004450
IEA
GOA Databaseisocitrate dehydrogenase (NADP+) activity
GO:0004450
IBA
Gene Ontologyisocitrate dehydrogenase (NADP+) activity1
GO:0004450
IEA
InterProisocitrate dehydrogenase (NADP+) activity
GO:0016491
IEA
GOA Databaseoxidoreductase activity
GO:0046872
IEA
GOA Databasemetal ion binding
GO:0000287
IEA
Gene Ontologymagnesium ion binding
GO:0051287
IEA
Gene OntologyNAD binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009507
IDA
IEA
GOA Databasechloroplast
GO:0009507
HDA
ISM
Gene Ontologychloroplast2
GO:0009536
IEA
GOA Databaseplastid
GO:0009536
HDA
Gene Ontologyplastid3
GO:0009534
IDA
GOA Databasechloroplast thylakoid
GO:0009534
HDA
Gene Ontologychloroplast thylakoid4
GO:0005739
IDA
IEA
GOA Databasemitochondrion
GO:0005739
HDA
IBA
Gene Ontologymitochondrion1 5
GO:0009570
IDA
GOA Databasechloroplast stroma
GO:0009570
HDA
Gene Ontologychloroplast stroma4
GO:0005829
HDA
Gene Ontologycytosol6

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR004790 Isocitrate dehydrogenase NADP-dependent
IPR024084 Isopropylmalate dehydrogenase-like domain
Mapman id Description
50.1.1 Enzyme classification.EC_1 oxidoreductases.EC_1.1 oxidoreductase acting on CH-OH group of donor