Gene: AT4G37930

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT4G37930
  • Transcript Identifier AT4G37930.1
  • Gene Type Coding gene
  • Location Chr4 : 17831891-17834742 : negative

Gene Family Information

  • ID HOM05D000575
  • #Genes/#Species 966/99
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT4G37930.1
  • symbol SHM1
  • Alias SHMT1,SERINE HYDROXYMETHYLTRANSFERASE 1,STM,SERINE TRANSHYDROXYMETHYLTRANSFERASE
  • uniprot Q9SZJ5

Descriptions

  • Description serine transhydroxymethyltransferase 1
  • Computational description serine transhydroxymethyltransferase 1 (SHM1); FUNCTIONS IN: poly(U) RNA binding, glycine hydroxymethyltransferase activity; INVOLVED IN: in 8 processes; LOCATED IN: in 9 components; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 17 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Serine hydroxymethyltransferase, pyridoxal phosphate binding site (InterPro:IPR019798), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Serine hydroxymethyltransferase (InterPro:IPR001085); BEST Arabidopsis thaliana protein match is: serine hydroxymethyltransferase 2 (TAIR:AT5G26780.1); Has 11621 Blast hits to 11596 proteins in 2825 species: Archae - 258; Bacteria - 6371; Metazoa - 337; Fungi - 287; Plants - 346; Viruses - 6; Other Eukaryotes - 4016 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0046655
IBA
Gene Ontologyfolic acid metabolic process1
GO:0046653
IBA
Gene Ontologytetrahydrofolate metabolic process1
GO:0019264
IEA
GOA Databaseglycine biosynthetic process from serine
GO:0019264
IBA
Gene Ontologyglycine biosynthetic process from serine1
GO:0019264
IEA
InterProglycine biosynthetic process from serine
GO:0006565
IBA
Gene OntologyL-serine catabolic process1
GO:0046686
IEP
GOA Databaseresponse to cadmium ion
GO:0006730
IEA
GOA Databaseone-carbon metabolic process
GO:0006730
IBA
Gene Ontologyone-carbon metabolic process1
GO:0035999
IEA
Gene Ontologytetrahydrofolate interconversion
GO:0035999
IEA
InterProtetrahydrofolate interconversion
GO:0007623
IEP
Gene Ontologycircadian rhythm2
GO:0009416
IEP
Gene Ontologyresponse to light stimulus2
GO:0009626
TAS
Gene Ontologyplant-type hypersensitive response3
GO:0009853
IMP
Gene Ontologyphotorespiration4
GO:0009409
IEP
Gene Ontologyresponse to cold5
GO:0019464
IMP
Gene Ontologyglycine decarboxylation via glycine cleavage system
GO:0006544
IDA
Gene Ontologyglycine metabolic process6
GO:0006563
IDA
Gene OntologyL-serine metabolic process6

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0030170
IEA
GOA Databasepyridoxal phosphate binding
GO:0030170
IBA
Gene Ontologypyridoxal phosphate binding1
GO:0030170
IEA
InterPropyridoxal phosphate binding
GO:0004372
IEA
GOA Databaseglycine hydroxymethyltransferase activity
GO:0004372
IDA
IBA
TAS
Gene Ontologyglycine hydroxymethyltransferase activity1 6 7
GO:0004372
IEA
InterProglycine hydroxymethyltransferase activity
GO:0070905
IBA
Gene Ontologyserine binding1
GO:0050897
IBA
Gene Ontologycobalt ion binding1
GO:0016740
IEA
GOA Databasetransferase activity
GO:0003824
IEA
GOA Databasecatalytic activity
GO:0003824
IEA
InterProcatalytic activity
GO:0005515
IPI
Gene Ontologyprotein binding8
GO:0008266
IDA
Gene Ontologypoly(U) RNA binding9
GO:0003729
IDA
Gene OntologymRNA binding10
GO:0008270
IBA
Gene Ontologyzinc ion binding1

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0022626
IDA
GOA Databasecytosolic ribosome
GO:0022626
HDA
Gene Ontologycytosolic ribosome11
GO:0005737
IEA
GOA Databasecytoplasm
GO:0005737
IBA
Gene Ontologycytoplasm1
GO:0005739
IEA
GOA Databasemitochondrion
GO:0005739
IDA, HDA
Gene Ontologymitochondrion8 12
GO:0009570
IDA
GOA Databasechloroplast stroma
GO:0009570
HDA
Gene Ontologychloroplast stroma13
GO:0005886
IDA
GOA Databaseplasma membrane
GO:0005886
HDA
Gene Ontologyplasma membrane14
GO:0048046
IDA
GOA Databaseapoplast
GO:0048046
HDA
Gene Ontologyapoplast15
GO:0009534
IDA
GOA Databasechloroplast thylakoid
GO:0009534
HDA
Gene Ontologychloroplast thylakoid13
GO:0005634
IDA
GOA Databasenucleus
GO:0005634
HDA
Gene Ontologynucleus16
GO:0005759
ISS
Gene Ontologymitochondrial matrix2
GO:0010319
IDA
Gene Ontologystromule5
GO:0005829
IDA, HDA
Gene Ontologycytosol17 18

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR015422 Pyridoxal phosphate-dependent transferase, small domain
IPR001085 Serine hydroxymethyltransferase
IPR015421 Pyridoxal phosphate-dependent transferase, major domain
IPR039429 Serine hydroxymethyltransferase-like domain
IPR015424 Pyridoxal phosphate-dependent transferase
Mapman id Description
1.3.5 Photosynthesis.photorespiration.serine hydroxymethyltransferase (SHM)