Gene: AT4G29130

General Information

Computational description hexokinase 1 (HXK1); FUNCTIONS IN: fructokinase activity, hexokinase activity, glucokinase activity, zinc ion binding, ATP binding; INVOLVED IN: sugar mediated signaling pathway, hexose catabolic process, glucose mediated signaling pathway, programmed cell death; LOCATED IN: in 6 components; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Hexokinase, N-terminal (InterPro:IPR022672), Hexokinase, conserved site (InterPro:IPR019807), Hexokinase, C-terminal (InterPro:IPR022673), Hexokinase (InterPro:IPR001312); BEST Arabidopsis thaliana protein match is: hexokinase 2 (TAIR:AT2G19860.1); Has 2426 Blast hits to 2148 proteins in 325 species: Archae - 0; Bacteria - 92; Metazoa - 1300; Fungi - 606; Plants - 290; Viruses - 0; Other Eukaryotes - 138 (source: NCBI BLink).

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0006357	IMP	GOA Database	regulation of transcription by RNA polymerase II
GO:0019318	IEA	GOA Database	hexose metabolic process
GO:0046835	IEA	GOA Database	carbohydrate phosphorylation
GO:0016310	IEA	GOA Database	phosphorylation
GO:0005975	IEA	GOA Database	carbohydrate metabolic process
GO:0005975	IEA	InterPro	carbohydrate metabolic process
GO:0001678	IEA	GOA Database	cellular glucose homeostasis
GO:0001678	IBA	Gene Ontology	cellular glucose homeostasis	1
GO:0001678	IEA	InterPro	cellular glucose homeostasis
GO:0009749	ISO	PLAZA Integrative Orthology	response to glucose	Os01g0742500
GO:0006096	IBA IEA	Gene Ontology	glycolytic process	1
GO:0019320	IDA	Gene Ontology	hexose catabolic process	2
GO:0010182	TAS	Gene Ontology	sugar mediated signaling pathway	3
GO:0010255	IMP	Gene Ontology	glucose mediated signaling pathway	4
GO:0012501	IMP	Gene Ontology	programmed cell death	5
GO:0009750	IMP	Gene Ontology	response to fructose	6
GO:0010148	IMP	Gene Ontology	transpiration	7
GO:0090332	IMP	Gene Ontology	stomatal closure	7
GO:2000032	IMP, IGI	Gene Ontology	regulation of secondary shoot formation	8
GO:0051156	IBA	Gene Ontology	glucose 6-phosphate metabolic process	1

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0004396	IEA	GOA Database	hexokinase activity
GO:0004396	IDA	Gene Ontology	hexokinase activity	2
GO:0004396	IEA	InterPro	hexokinase activity
GO:0004340	IEA	GOA Database	glucokinase activity
GO:0004340	IDA IBA	Gene Ontology	glucokinase activity	1 2
GO:0008865	IEA	GOA Database	fructokinase activity
GO:0008865	IDA IBA	Gene Ontology	fructokinase activity	1 2
GO:0008270	IDA	GOA Database	zinc ion binding
GO:0008270	HDA	Gene Ontology	zinc ion binding	9
GO:0000166	IEA	GOA Database	nucleotide binding
GO:0016740	IEA	GOA Database	transferase activity
GO:0001046	IMP	GOA Database	core promoter sequence-specific DNA binding
GO:0005524	IEA	GOA Database	ATP binding
GO:0005524	IEA	InterPro	ATP binding
GO:0016301	IEA	GOA Database	kinase activity
GO:0016773	IEA	GOA Database	phosphotransferase activity, alcohol group as acceptor
GO:0016773	IEA	InterPro	phosphotransferase activity, alcohol group as acceptor
GO:0005536	IEA	Gene Ontology	glucose binding
GO:0005536	IEA	InterPro	glucose binding
GO:0005515	IPI	Gene Ontology	protein binding	10
GO:0019158	IBA	Gene Ontology	mannokinase activity	1

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0016021	IEA	GOA Database	integral component of membrane
GO:0005634	IEA	GOA Database	nucleus
GO:0005634	IDA	Gene Ontology	nucleus	11
GO:0005741	IEA	GOA Database	mitochondrial outer membrane
GO:0005774	IDA	GOA Database	vacuolar membrane
GO:0005773	IDA	GOA Database	vacuole
GO:0009536	IDA	GOA Database	plastid
GO:0005739	IEA	GOA Database	mitochondrion
GO:0005739	IDA, HDA ISM, IBA TAS	Gene Ontology	mitochondrion	1 5 12 13
GO:0016020	IEA	GOA Database	membrane
GO:0000325	HDA	Gene Ontology	plant-type vacuole	14
GO:0005829	IBA	Gene Ontology	cytosol	1
GO:0032991	IMP	GOA Database	protein-containing complex

Experimental Evidence

Computational Reviewed Evidence

Electronic Evidence

InterPro	Description
IPR022673	Hexokinase, C-terminal
IPR043129	ATPase, nucleotide binding domain
IPR022672	Hexokinase, N-terminal
IPR001312	Hexokinase

Mapman id	Description
3.1.4.3	Carbohydrate metabolism.sucrose metabolism.degradation.hexokinase