Gene: AT4G21540

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT4G21540
  • Transcript Identifier AT4G21540.1
  • Gene Type Coding gene
  • Location Chr4 : 11459609-11462356 : positive

Gene Family Information

  • ID HOM05D004176
  • #Genes/#Species 169/93
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT4G21540.1
  • symbol SPHK1
  • uniprot Q8L7L1

Descriptions

  • Description sphingosine kinase 1
  • Computational description sphingosine kinase 1 (SPHK1); FUNCTIONS IN: diacylglycerol kinase activity, sphinganine kinase activity, D-erythro-sphingosine kinase activity; INVOLVED IN: activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway, seed germination, response to abscisic acid stimulus; LOCATED IN: plant-type vacuole membrane, vacuole; CONTAINS InterPro DOMAIN/s: Diacylglycerol kinase, catalytic domain (InterPro:IPR001206); BEST Arabidopsis thaliana protein match is: Diacylglycerol kinase family protein (TAIR:AT4G21534.1); Has 6888 Blast hits to 3984 proteins in 1156 species: Archae - 1; Bacteria - 4291; Metazoa - 1136; Fungi - 331; Plants - 472; Viruses - 0; Other Eukaryotes - 657 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0046512
IBA
Gene Ontologysphingosine biosynthetic process1
GO:0016310
IEA
GOA Databasephosphorylation
GO:0016310
IBA
Gene Ontologyphosphorylation1
GO:0046834
IEA
GOA Databaselipid phosphorylation
GO:0006665
IDA, IMP
IBA
Gene Ontologysphingolipid metabolic process1 2 3
GO:0071215
IMP
Gene Ontologycellular response to abscisic acid stimulus3
GO:0009845
IMP
Gene Ontologyseed germination4
GO:0009737
IMP
Gene Ontologyresponse to abscisic acid4

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
GOA Databasenucleotide binding
GO:0008481
IEA
GOA Databasesphinganine kinase activity
GO:0008481
IDA
Gene Ontologysphinganine kinase activity4
GO:0016740
IEA
GOA Databasetransferase activity
GO:0005524
IEA
GOA DatabaseATP binding
GO:0016301
IEA
GOA Databasekinase activity
GO:0016301
IEA
InterProkinase activity
GO:0003951
IEA
Gene OntologyNAD+ kinase activity
GO:0003951
IEA
InterProNAD+ kinase activity
GO:0001727
IBA
Gene Ontologylipid kinase activity1
GO:0017050
IDA
TAS
Gene OntologyD-erythro-sphingosine kinase activity4 5

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IBA
Gene Ontologycytoplasm1
GO:0005774
IEA
GOA Databasevacuolar membrane
GO:0005773
IDA
IEA
GOA Databasevacuole
GO:0043231
IBA
Gene Ontologyintracellular membrane-bounded organelle1
GO:0016020
IEA
GOA Databasemembrane
GO:0016020
IBA
Gene Ontologymembrane1
GO:0009705
IDA
Gene Ontologyplant-type vacuole membrane6
GO:0000325
HDA
Gene Ontologyplant-type vacuole7
GO:0009507
ISM
Gene Ontologychloroplast
GO:0005634
ISM
Gene Ontologynucleus

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR001206 Diacylglycerol kinase, catalytic domain
IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily
IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal
Mapman id Description
5.7.5.3 Lipid metabolism.lipid degradation.sphingolipid degradation.sphingosine kinase