Gene: AT4G16340

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT4G16340
  • Transcript Identifier AT4G16340.1
  • Gene Type Coding gene
  • Location Chr4 : 9228773-9241060 : negative

Gene Family Information

  • ID HOM05D003504
  • #Genes/#Species 194/96
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT4G16340.1
  • symbol SPK1
  • full_name SPIKE1
  • uniprot Q8SAB7

Descriptions

  • Description guanyl-nucleotide exchange factors;GTPase binding;GTP binding protein
  • Computational description SPIKE1 (SPK1); FUNCTIONS IN: GTPase binding, GTP binding, guanyl-nucleotide exchange factor activity; LOCATED IN: cytosol, plasma membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Dedicator of cytokinesis (InterPro:IPR010703); Has 1667 Blast hits to 1104 proteins in 136 species: Archae - 0; Bacteria - 0; Metazoa - 1334; Fungi - 77; Plants - 63; Viruses - 0; Other Eukaryotes - 193 (source: NCBI BLink).
  • Loading (ortholog descriptions from ath)...

Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0010928
IMP
Gene Ontologyregulation of auxin mediated signaling pathway1
GO:0007264
IEA
Gene Ontologysmall GTPase mediated signal transduction
GO:0007264
IEA
InterProsmall GTPase mediated signal transduction
GO:0009734
IEA
GOA Databaseauxin-activated signaling pathway
GO:0050790
IEA
GOA Databaseregulation of catalytic activity
GO:0009958
IMP
Gene Ontologypositive gravitropism1
GO:0016192
IMP
Gene Ontologyvesicle-mediated transport2
GO:0008064
IMP
Gene Ontologyregulation of actin polymerization or depolymerization3
GO:0051493
IMP
Gene Ontologyregulation of cytoskeleton organization4
GO:0008360
IMP
Gene Ontologyregulation of cell shape4

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005085
IEA
GOA Databaseguanyl-nucleotide exchange factor activity
GO:0005085
IDA
Gene Ontologyguanyl-nucleotide exchange factor activity5
GO:0005085
IEA
InterProguanyl-nucleotide exchange factor activity
GO:0005515
IPI
Gene Ontologyprotein binding5

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005783
IEA
GOA Databaseendoplasmic reticulum
GO:0016020
IEA
GOA Databasemembrane
GO:0005829
IDA
GOA Databasecytosol
GO:0005829
RCA
Gene Ontologycytosol6
GO:0005886
IDA
GOA Databaseplasma membrane
GO:0005789
IEA
GOA Databaseendoplasmic reticulum membrane
GO:0005634
IEA
GOA Databasenucleus
GO:0005634
IDA
ISM
Gene Ontologynucleus2
GO:0005737
IEA
GOA Databasecytoplasm
GO:0070971
IDA
Gene Ontologyendoplasmic reticulum exit site2
GO:0019898
IDA
Gene Ontologyextrinsic component of membrane2

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR043161 Dedicator of cytokinesis, C-terminal, lobe A
IPR026791 Dedicator of cytokinesis
IPR043162 Dedicator of cytokinesis, C-terminal, lobe C
IPR027007 C2 DOCK-type domain
IPR027357 DOCKER domain
IPR035892 C2 domain superfamily
Mapman id Description
27.4.3.2 Multi-process regulation.Rop-GTPase regulatory system.RopGEF guanine nucleotide exchange factor activities.exchange factor (DHR2)