Gene: AT4G12010

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT4G12010
  • Transcript Identifier AT4G12010.1
  • Gene Type Coding gene
  • Location Chr4 : 7197325-7201393 : negative

Gene Family Information

  • ID HOM05D000005
  • #Genes/#Species 11550/84
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT4G12010.1
  • uniprot Q9SZ66

Descriptions

  • Description Disease resistance protein (TIR-NBS-LRR class) family
  • Computational description Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, ATP binding; INVOLVED IN: signal transduction, apoptosis, defense response, innate immune response; LOCATED IN: intrinsic to membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) (TAIR:AT4G19510.1); Has 31049 Blast hits to 21052 proteins in 960 species: Archae - 20; Bacteria - 2553; Metazoa - 5096; Fungi - 331; Plants - 21936; Viruses - 4; Other Eukaryotes - 1109 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006952
IEA
GOA Databasedefense response
GO:0006952
IEA
InterProdefense response
GO:0007165
IEA
Gene Ontologysignal transduction
GO:0007165
IEA
InterProsignal transduction
GO:0009626
IEA
GOA Databaseplant-type hypersensitive response
GO:0042742
IMP
Gene Ontologydefense response to bacterium1

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016787
IEA
GOA Databasehydrolase activity
GO:0003953
IEA
GOA DatabaseNAD+ nucleosidase activity
GO:0003953
IEA
InterProNAD+ nucleosidase activity
GO:0043531
IEA
Gene OntologyADP binding
GO:0043531
IEA
InterProADP binding
GO:0005515
IPI
Gene Ontologyprotein binding1
GO:0005515
IEA
InterProprotein binding
GO:0005524
IEA
GOA DatabaseATP binding
GO:0000166
IEA
GOA Databasenucleotide binding
GO:0061809
IEA
Gene OntologyNAD+ nucleotidase, cyclic ADP-ribose generating
GO:0050135
IEA
Gene OntologyNAD(P)+ nucleosidase activity

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR001611 Leucine-rich repeat
IPR002182 NB-ARC
IPR027417 P-loop containing nucleoside triphosphate hydrolase
IPR000157 Toll/interleukin-1 receptor homology (TIR) domain
IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily
IPR011713 Leucine-rich repeat 3
IPR044974 Disease resistance protein, plants
IPR036390 Winged helix DNA-binding domain superfamily
IPR032675 Leucine-rich repeat domain superfamily
IPR042197 Apoptotic protease-activating factors, helical domain
Mapman id Description
26.9.2.1.1 External stimuli response.pathogen.effector-triggered immunity (ETI) network.TNL-mediated effector-triggered immunity.effector receptor (NLR)