InterPro domain: IPR044974

General Information

  • Identifier IPR044974
  • Description Disease resistance protein, plants
  • Number of genes 26233
  • Gene duplication stats Loading...
  • Associated GO terms GO:0006952  

Abstract

Plants are attacked by a range of phytopathogenic organisms, including viruses, mycoplasma, bacteria, fungi, nematodes, protozoa and parasites. Resistance to a pathogen is manifested in several ways and is often correlated with a hypersensitive response (HR), localised induced cell death in the host plant at the site of infection [ 1 ]. The induction of the plant defence response that leads to HR is initiated by the plants recognition of specific signal molecules (elicitors) produced by the pathogen; R genes are thought to encode receptors for these elicitors. RPS2, N and L6 genes confer resistance to bacterial, viral and fungal pathogens.

Sequence analysis has shown that they contain C-terminal leucine-rich repeats, which are characteristic of plant and animal proteins involved in protein-protein interactions [ 2 ]. In addition, the sequences contain a conserved nucleotide-binding site towards their N-terminal.

This entry represents a group of plant disease resistance proteins.


1. Molecular genetics of plant disease resistance. Science 268, 661-7

Species distribution

Gene table

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