InterPro domain: IPR044974
General Information
- Identifier IPR044974
- Description Disease resistance protein, plants
- Number of genes 26233
- Gene duplication stats Loading...
- Associated GO terms GO:0006952
Abstract
Plants are attacked by a range of phytopathogenic organisms, including viruses, mycoplasma, bacteria, fungi, nematodes, protozoa and parasites. Resistance to a pathogen is manifested in several ways and is often correlated with a hypersensitive response (HR), localised induced cell death in the host plant at the site of infection [ 1 ]. The induction of the plant defence response that leads to HR is initiated by the plants recognition of specific signal molecules (elicitors) produced by the pathogen; R genes are thought to encode receptors for these elicitors. RPS2, N and L6 genes confer resistance to bacterial, viral and fungal pathogens.
Sequence analysis has shown that they contain C-terminal leucine-rich repeats, which are characteristic of plant and animal proteins involved in protein-protein interactions [ 2 ]. In addition, the sequences contain a conserved nucleotide-binding site towards their N-terminal.
This entry represents a group of plant disease resistance proteins.1. Molecular genetics of plant disease resistance. Science 268, 661-7