Gene: AT4G02650

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT4G02650
  • Transcript Identifier AT4G02650.1
  • Gene Type Coding gene
  • Location Chr4 : 1156539-1158543 : positive

Gene Family Information

  • ID HOM05D000291
  • #Genes/#Species 1525/99
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT4G02650.1
  • uniprot Q8GX47

Descriptions

  • Description ENTH/ANTH/VHS superfamily protein
  • Computational description ENTH/ANTH/VHS superfamily protein; FUNCTIONS IN: phospholipid binding, clathrin binding, binding, phosphatidylinositol binding; INVOLVED IN: clathrin coat assembly; LOCATED IN: clathrin coat; EXPRESSED IN: male gametophyte, pollen tube; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage; CONTAINS InterPro DOMAIN/s: Epsin-like, N-terminal (InterPro:IPR013809), ANTH (InterPro:IPR011417), ENTH/VHS (InterPro:IPR008942), Clathrin adaptor, phosphoinositide-binding, GAT-like (InterPro:IPR014712); BEST Arabidopsis thaliana protein match is: ENTH/ANTH/VHS superfamily protein (TAIR:AT1G03050.1); Has 1450 Blast hits to 1384 proteins in 224 species: Archae - 6; Bacteria - 69; Metazoa - 513; Fungi - 180; Plants - 407; Viruses - 6; Other Eukaryotes - 269 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0048268
IEA
Gene Ontologyclathrin coat assembly
GO:0048268
IEA
InterProclathrin coat assembly
GO:0006897
IEA
GOA Databaseendocytosis
GO:0006900
IBA
Gene Ontologyvesicle budding from membrane1
GO:0072583
IBA
Gene Ontologyclathrin-dependent endocytosis1
GO:0072659
IGI
Gene Ontologyprotein localization to plasma membrane2
GO:0009860
IGI
Gene Ontologypollen tube growth2

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005545
IEA
GOA Database1-phosphatidylinositol binding
GO:0005545
IBA
Gene Ontology1-phosphatidylinositol binding1
GO:0005545
IEA
InterPro1-phosphatidylinositol binding
GO:0005543
IEA
GOA Databasephospholipid binding
GO:0005543
IEA
InterProphospholipid binding
GO:0030276
IEA
GOA Databaseclathrin binding
GO:0030276
IEA
InterProclathrin binding
GO:0000149
IBA
Gene OntologySNARE binding1
GO:0032050
IBA
Gene Ontologyclathrin heavy chain binding1
GO:0005546
IBA
Gene Ontologyphosphatidylinositol-4,5-bisphosphate binding1

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0030136
IEA
GOA Databaseclathrin-coated vesicle
GO:0030136
IBA
Gene Ontologyclathrin-coated vesicle1
GO:0030136
IEA
InterProclathrin-coated vesicle
GO:0016020
IEA
GOA Databasemembrane
GO:0031410
IEA
GOA Databasecytoplasmic vesicle
GO:0005905
IEA
GOA Databaseclathrin-coated pit
GO:0005905
IBA
Gene Ontologyclathrin-coated pit1
GO:0005794
IEA
GOA DatabaseGolgi apparatus
GO:0005634
ISM
Gene Ontologynucleus
GO:0090406
IDA
Gene Ontologypollen tube2
GO:0090404
IDA
Gene Ontologypollen tube tip2
GO:0045334
IDA
Gene Ontologyclathrin-coated endocytic vesicle2

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR014712 ANTH domain superfamily
IPR013809 ENTH domain
IPR011417 AP180 N-terminal homology (ANTH) domain
IPR008942 ENTH/VHS
Mapman id Description
22.3.1.8.2 Vesicle trafficking.post-Golgi trafficking.clathrin coated vesicle (CCV) machinery.CCV accessory factor activities.adaptor protein (ECA1/2)