Gene: AT4G02580

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT4G02580
  • Transcript Identifier AT4G02580.1
  • Gene Type Coding gene
  • Location Chr4 : 1134586-1136906 : positive

Gene Family Information

  • ID HOM05D000319
  • #Genes/#Species 1449/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT4G02580.1
  • uniprot O22769

Descriptions

  • Description NADH-ubiquinone oxidoreductase 24 kDa subunit
  • Computational description NADH-ubiquinone oxidoreductase 24 kDa subunit, putative; FUNCTIONS IN: NADH dehydrogenase (ubiquinone) activity, zinc ion binding; INVOLVED IN: response to oxidative stress, mitochondrial electron transport, NADH to ubiquinone; LOCATED IN: mitochondrion, mitochondrial respiratory chain complex I, respiratory chain complex I; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), NADH:ubiquinone oxidoreductase, 24kDa subunit (InterPro:IPR002023), Thioredoxin-like fold (InterPro:IPR012336); Has 5564 Blast hits to 5564 proteins in 1535 species: Archae - 26; Bacteria - 3396; Metazoa - 195; Fungi - 114; Plants - 49; Viruses - 0; Other Eukaryotes - 1784 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006511
ISO
PLAZA Homology (enrichment)ubiquitin-dependent protein catabolic process HOM05D000319
GO:0006979
IDA
GOA Databaseresponse to oxidative stress
GO:0006120
IBA
Gene Ontologymitochondrial electron transport, NADH to ubiquinone1

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008270
IDA
GOA Databasezinc ion binding
GO:0008270
HDA
Gene Ontologyzinc ion binding2
GO:0031625
ISO
PLAZA Homology (enrichment)ubiquitin protein ligase binding HOM05D000319
GO:0016491
IEA
GOA Databaseoxidoreductase activity
GO:0016491
IEA
InterProoxidoreductase activity
GO:0046872
IEA
GOA Databasemetal ion binding
GO:0051536
IEA
GOA Databaseiron-sulfur cluster binding
GO:0051537
IEA
GOA Database2 iron, 2 sulfur cluster binding
GO:0008137
IEA
Gene OntologyNADH dehydrogenase (ubiquinone) activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016020
IEA
GOA Databasemembrane
GO:0005739
IEA
GOA Databasemitochondrion
GO:0005739
IDA, HDA
ISM
Gene Ontologymitochondrion3 4
GO:0070469
IEA
GOA Databaserespirasome
GO:0005743
IEA
GOA Databasemitochondrial inner membrane
GO:0005747
IDA, HDA
IBA
Gene Ontologymitochondrial respiratory chain complex I1 5 6
GO:0005829
HDA
Gene Ontologycytosol7

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR042128 NuoE domain
IPR002023 NADH-quinone oxidoreductase subunit E-like
IPR041921 NADH-quinone oxidoreductase subunit E, N-terminal
IPR036249 Thioredoxin-like superfamily
Mapman id Description
2.4.1.1.2 Cellular respiration.oxidative phosphorylation.NADH dehydrogenase complex.module N (electron input).component NQO2