Gene: AT4G00020

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT4G00020
  • Transcript Identifier AT4G00020.2
  • Gene Type Coding gene
  • Location Chr4 : 2895-10364 : negative

Gene Family Information

  • ID HOM05D005064
  • #Genes/#Species 148/93
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT4G00020.2
  • symbol BRCA2(IV)
  • Alias BRCA2(IV),BREAST CANCER 2 like 2A,BRCA2A,EDA20,EMBRYO SAC DEVELOPMENT ARREST 20,MEE43,MATERNAL EFFECT EMBRYO ARREST 43
  • uniprot Q7Y1C5

Descriptions

  • Description BREAST CANCER 2 like 2A
  • Computational description BREAST CANCER 2 like 2A (BRCA2(IV)); FUNCTIONS IN: single-stranded DNA binding; INVOLVED IN: meiosis, embryo sac morphogenesis, embryo sac development, embryo development ending in seed dormancy; LOCATED IN: nucleus; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), DNA recombination/repair protein BRCA2, helical domain (InterPro:IPR015252), DNA recombination and repair protein, BRCA2 (InterPro:IPR011370), BRCA2, oligonucleotide/oligosaccharide-binding 1 (InterPro:IPR015187), Breast cancer type 2 susceptibility protein (InterPro:IPR015525), BRCA2 repeat (InterPro:IPR002093); BEST Arabidopsis thaliana protein match is: BRCA2-like B (TAIR:AT5G01630.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
  • Computational description BREAST CANCER 2 like 2A (BRCA2(IV)); FUNCTIONS IN: single-stranded DNA binding; INVOLVED IN: meiosis, embryo sac morphogenesis, embryo sac development, embryo development ending in seed dormancy; LOCATED IN: nucleus; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), DNA recombination/repair protein BRCA2, helical domain (InterPro:IPR015252), DNA recombination and repair protein, BRCA2 (InterPro:IPR011370), Breast cancer type 2 susceptibility protein (InterPro:IPR015525), BRCA2, oligonucleotide/oligosaccharide-binding 1 (InterPro:IPR015187), BRCA2 repeat (InterPro:IPR002093); BEST Arabidopsis thaliana protein match is: BRCA2-like B (TAIR:AT5G01630.1); Has 319 Blast hits to 211 proteins in 92 species: Archae - 0; Bacteria - 11; Metazoa - 140; Fungi - 22; Plants - 61; Viruses - 0; Other Eukaryotes - 85 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006310
IEA
GOA DatabaseDNA recombination
GO:0006281
IEA
GOA DatabaseDNA repair
GO:0006281
IEA
InterProDNA repair
GO:0000724
IBA
GOA Databasedouble-strand break repair via homologous recombination
GO:0000724
IGI
IEA
Gene Ontologydouble-strand break repair via homologous recombination1
GO:0000724
IEA
InterProdouble-strand break repair via homologous recombination
GO:0006355
IBA
GOA Databaseregulation of transcription, DNA-templated
GO:0006355
IGI
Gene Ontologyregulation of transcription, DNA-templated2
GO:0051321
IEA
GOA Databasemeiotic cell cycle
GO:0007049
IEA
GOA Databasecell cycle
GO:0006974
IEA
GOA Databasecellular response to DNA damage stimulus
GO:0031347
IGI
Gene Ontologyregulation of defense response2
GO:0048314
IMP
Gene Ontologyembryo sac morphogenesis3
GO:0009793
IMP
Gene Ontologyembryo development ending in seed dormancy3
GO:0009553
IMP
Gene Ontologyembryo sac development3

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003677
IEA
GOA DatabaseDNA binding
GO:0005515
IPI
Gene Ontologyprotein binding4

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005739
ISO
PLAZA Integrative Orthologymitochondrion AT5G01630
GO:0005634
ISM
Gene Ontologynucleus

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR012340 Nucleic acid-binding, OB-fold
IPR015187 BRCA2, OB1
IPR015525 Breast cancer type 2 susceptibility protein
IPR015252 Breast cancer type 2 susceptibility protein, helical domain
IPR036315 BRCA2 helical domain superfamily
IPR002093 BRCA2 repeat
Mapman id Description
13.3.5.4.2 Cell cycle organisation.mitosis and meiosis.meiotic recombination.DNA strand exchange.DMC1-recruitment protein (BRCA2)
14.3.2.1 DNA damage response.homologous recombination repair (HR).BRCC DNA-damage response complex.component BRCA2