Gene: AT3G57050
General Information
Structural Information
- Species Arabidopsis thaliana
- Gene Identifier AT3G57050
- Transcript Identifier AT3G57050.2
- Gene Type Coding gene
- Location Chr3 : 21111939-21114521 : negative
Gene Family Information
- ID HOM05D001730
- #Genes/#Species 374/99
- Phylogenetic origin
- ID ORTHO05D005730
- #Genes/#Species 153/93
- Phylogenetic origin
Gene Duplication Information
Labels
Identifiers
- tid AT3G57050.2
- symbol CBL
- uniprot P53780
Descriptions
- Description cystathionine beta-lyase
- Computational description cystathionine beta-lyase (CBL); FUNCTIONS IN: cystathionine beta-lyase activity; INVOLVED IN: L-methionine biosynthetic process from L-homoserine via cystathionine; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Cystathionine beta-lyase, eukaryotic (InterPro:IPR006238), Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (InterPro:IPR000277), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421); BEST Arabidopsis thaliana protein match is: Pyridoxal phosphate (PLP)-dependent transferases superfamily protein (TAIR:AT3G01120.1); Has 21174 Blast hits to 21168 proteins in 2454 species: Archae - 221; Bacteria - 12373; Metazoa - 223; Fungi - 823; Plants - 274; Viruses - 1; Other Eukaryotes - 7259 (source: NCBI BLink).
- Computational description cystathionine beta-lyase (CBL); FUNCTIONS IN: cystathionine beta-lyase activity; INVOLVED IN: L-methionine biosynthetic process from L-homoserine via cystathionine; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (InterPro:IPR000277), Cystathionine beta-lyase, eukaryotic (InterPro:IPR006238), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422); BEST Arabidopsis thaliana protein match is: Pyridoxal phosphate (PLP)-dependent transferases superfamily protein (TAIR:AT3G01120.1); Has 21173 Blast hits to 21167 proteins in 2454 species: Archae - 221; Bacteria - 12375; Metazoa - 223; Fungi - 823; Plants - 274; Viruses - 1; Other Eukaryotes - 7256 (source: NCBI BLink).
- Loading (ortholog descriptions from ath)...
Functional Annotation
Biological Process
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0019346 | IBA IEA | Gene Ontology | transsulfuration | 1 |
| GO:0019346 | IEA | InterPro | transsulfuration | |
| GO:0008652 | IEA | GOA Database | cellular amino acid biosynthetic process | |
| GO:0009086 | IEA | GOA Database | methionine biosynthetic process | |
| GO:0071266 | IEA | Gene Ontology | 'de novo' L-methionine biosynthetic process | |
| GO:0071266 | IEA | InterPro | 'de novo' L-methionine biosynthetic process | |
| GO:0009414 | ISO | PLAZA Integrative Orthology | response to water deprivation | Solyc10g079720.2 |
| GO:0019343 | IBA | Gene Ontology | cysteine biosynthetic process via cystathionine | 1 |
| GO:0019279 | TAS | Gene Ontology | L-methionine biosynthetic process from L-homoserine via cystathionine | 2 |
Molecular Function
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0003824 | IEA | GOA Database | catalytic activity | |
| GO:0003824 | IEA | InterPro | catalytic activity | |
| GO:0004123 | IBA | Gene Ontology | cystathionine gamma-lyase activity | 1 |
| GO:0016829 | IEA | GOA Database | lyase activity | |
| GO:0004121 | IMP IEA | Gene Ontology | cystathionine beta-lyase activity | 3 |
| GO:0004121 | IEA | InterPro | cystathionine beta-lyase activity | |
| GO:0030170 | IBA IEA | Gene Ontology | pyridoxal phosphate binding | 1 |
| GO:0030170 | IEA | InterPro | pyridoxal phosphate binding | |
| GO:0003962 | ISO | PLAZA Homology (enrichment) | cystathionine gamma-synthase activity | HOM05D001730 |
| GO:0016846 | IBA | Gene Ontology | carbon-sulfur lyase activity | 1 |
| GO:0047804 | IEA | Gene Ontology | cysteine-S-conjugate beta-lyase activity |
Cellular Component
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0009507 | IEA | GOA Database | chloroplast | |
| GO:0009507 | IDA, HDA ISS, ISM | Gene Ontology | chloroplast | 2 3 4 |
| GO:0009570 | IDA | GOA Database | chloroplast stroma | |
| GO:0009570 | HDA | Gene Ontology | chloroplast stroma | 5 |
| GO:0009536 | IEA | GOA Database | plastid | |
| GO:0005737 | ISM, IBA | Gene Ontology | cytoplasm | 1 |
Color Legend
| Experimental Evidence |
| Computational Reviewed Evidence |
| Electronic Evidence |
| InterPro | Description |
|---|---|
| IPR006238 | Cystathionine beta-lyase, eukaryotic |
| IPR015422 | Pyridoxal phosphate-dependent transferase, small domain |
| IPR015424 | Pyridoxal phosphate-dependent transferase |
| IPR015421 | Pyridoxal phosphate-dependent transferase, major domain |
| IPR000277 | Cys/Met metabolism, pyridoxal phosphate-dependent enzyme |
| Mapman id | Description |
|---|---|
| 4.1.2.2.6.1.2 | Amino acid metabolism.biosynthesis.aspartate family.aspartate-derived amino acids.methionine.transsulfuration pathway.cystathionine beta-lyase |