Gene: AT3G44400
General Information
Structural Information
- Species Arabidopsis thaliana
- Gene Identifier AT3G44400
- Transcript Identifier AT3G44400.2
- Gene Type Coding gene
- Location Chr3 : 16046331-16049668 : negative
Gene Family Information
- ID HOM05D000005
- #Genes/#Species 11550/84
- Phylogenetic origin
- ID ORTHO05D000449
- #Genes/#Species 918/14
- Phylogenetic origin
Gene Duplication Information
- Tandem Duplication Tandem duplicate
Labels
Identifiers
- tid AT3G44400.2
- uniprot Q9M285
Descriptions
- Description Disease resistance protein (TIR-NBS-LRR class) family
- Computational description Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: signal transduction, defense response, apoptosis, innate immune response; LOCATED IN: intrinsic to membrane, endomembrane system; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT3G44630.3); Has 26520 Blast hits to 18063 proteins in 713 species: Archae - 22; Bacteria - 2368; Metazoa - 1818; Fungi - 184; Plants - 20768; Viruses - 6; Other Eukaryotes - 1354 (source: NCBI BLink).
- Computational description Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: signal transduction, apoptosis, defense response, innate immune response; LOCATED IN: intrinsic to membrane, endomembrane system; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT3G44630.3); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
- Loading (ortholog descriptions from ath)...
Functional Annotation
Biological Process
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0006952 | IEA | GOA Database | defense response | |
| GO:0006952 | IEA | InterPro | defense response | |
| GO:0050832 | ISO | PLAZA Integrative Orthology | defense response to fungus | AT3G44480 |
| GO:0002758 | ISO | PLAZA Integrative Orthology | innate immune response-activating signal transduction | AT3G44480 |
| GO:0002239 | ISO | PLAZA Integrative Orthology | response to oomycetes | AT3G44480 |
| GO:0034052 | ISO | PLAZA Integrative Orthology | positive regulation of plant-type hypersensitive response | AT3G44480 |
| GO:0007165 | IEA | Gene Ontology | signal transduction | |
| GO:0007165 | IEA | InterPro | signal transduction |
Molecular Function
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0140376 | ISO | PLAZA Integrative Orthology | innate immune receptor activity | AT3G44480 |
| GO:0003953 | IEA | Gene Ontology | NAD+ nucleosidase activity | |
| GO:0003953 | IEA | InterPro | NAD+ nucleosidase activity | |
| GO:0043531 | IEA | Gene Ontology | ADP binding | |
| GO:0043531 | IEA | InterPro | ADP binding | |
| GO:0016787 | IEA | GOA Database | hydrolase activity |
Cellular Component
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0005886 | ISO | PLAZA Integrative Orthology | plasma membrane | AT3G44480 |
| GO:0000139 | ISO | PLAZA Integrative Orthology | Golgi membrane | AT3G44480 |
| GO:0005789 | ISO | PLAZA Integrative Orthology | endoplasmic reticulum membrane | AT3G44480 |
| GO:0005737 | ISM | Gene Ontology | cytoplasm |
Color Legend
| Experimental Evidence |
| Computational Reviewed Evidence |
| Electronic Evidence |
| InterPro | Description |
|---|---|
| IPR011713 | Leucine-rich repeat 3 |
| IPR000157 | Toll/interleukin-1 receptor homology (TIR) domain |
| IPR035897 | Toll/interleukin-1 receptor homology (TIR) domain superfamily |
| IPR002182 | NB-ARC |
| IPR036390 | Winged helix DNA-binding domain superfamily |
| IPR042197 | Apoptotic protease-activating factors, helical domain |
| IPR003593 | AAA+ ATPase domain |
| IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| IPR044974 | Disease resistance protein, plants |
| IPR032675 | Leucine-rich repeat domain superfamily |
| Mapman id | Description |
|---|---|
| 26.9.2.1.1 | External stimuli response.pathogen.effector-triggered immunity (ETI) network.TNL-mediated effector-triggered immunity.effector receptor (NLR) |