Gene: AT3G28030

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT3G28030
  • Transcript Identifier AT3G28030.1
  • Gene Type Coding gene
  • Location Chr3 : 10424321-10431178 : positive

Gene Family Information

  • ID HOM05D005583
  • #Genes/#Species 138/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT3G28030.1
  • symbol UVH3
  • Alias UVR1,UV REPAIR DEFECTIVE 1
  • full_name ULTRAVIOLET HYPERSENSITIVE 3
  • uniprot Q9ATY5

Descriptions

  • Description 5'-3' exonuclease family protein
  • Computational description ULTRAVIOLET HYPERSENSITIVE 3 (UVH3); FUNCTIONS IN: protein binding, nuclease activity; INVOLVED IN: DNA repair, response to UV-B, response to heat, non-photoreactive DNA repair; LOCATED IN: nucleus; EXPRESSED IN: stem, leaf whorl, seed; EXPRESSED DURING: E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: XPG conserved site (InterPro:IPR019974), Xeroderma pigmentosum group G protein (InterPro:IPR001044), XPG N-terminal (InterPro:IPR006085), DNA repair protein (XPGC)/yeast Rad (InterPro:IPR006084), 5'-3' exonuclease, C-terminal subdomain (InterPro:IPR020045), Helix-hairpin-helix motif, class 2 (InterPro:IPR008918), XPG/RAD2 endonuclease (InterPro:IPR006086); BEST Arabidopsis thaliana protein match is: 5'-3' exonuclease family protein (TAIR:AT1G01880.1); Has 8115 Blast hits to 5779 proteins in 624 species: Archae - 528; Bacteria - 414; Metazoa - 2441; Fungi - 1496; Plants - 576; Viruses - 71; Other Eukaryotes - 2589 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006974
IEA
GOA Databasecellular response to DNA damage stimulus
GO:0006289
IEA
Gene Ontologynucleotide-excision repair
GO:0006289
IEA
InterPronucleotide-excision repair
GO:0006281
IEA
GOA DatabaseDNA repair
GO:0090305
IEA
GOA Databasenucleic acid phosphodiester bond hydrolysis
GO:0010213
IMP
Gene Ontologynon-photoreactive DNA repair1
GO:0009408
IMP
Gene Ontologyresponse to heat2
GO:0010224
IGI
Gene Ontologyresponse to UV-B3

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004519
IEA
Gene Ontologyendonuclease activity
GO:0004519
IEA
InterProendonuclease activity
GO:0003697
IEA
Gene Ontologysingle-stranded DNA binding
GO:0003697
IEA
InterProsingle-stranded DNA binding
GO:0004518
IEA
GOA Databasenuclease activity
GO:0004518
IEA
InterPronuclease activity
GO:0003824
IEA
GOA Databasecatalytic activity
GO:0003824
IEA
InterProcatalytic activity
GO:0003677
IEA
Gene OntologyDNA binding
GO:0003677
IEA
InterProDNA binding
GO:0016788
IEA
GOA Databasehydrolase activity, acting on ester bonds
GO:0016787
IEA
GOA Databasehydrolase activity
GO:0046872
IEA
GOA Databasemetal ion binding
GO:0017108
IBA
Gene Ontology5'-flap endonuclease activity4
GO:0005515
IPI
Gene Ontologyprotein binding5

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
GOA Databasenucleus
GO:0005634
ISM
Gene Ontologynucleus
GO:0005634
IEA
InterPronucleus

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR008918 Helix-hairpin-helix motif, class 2
IPR036279 5'-3' exonuclease, C-terminal domain superfamily
IPR025527 HUWE1/Rev1, ubiquitin binding region
IPR006084 XPG/Rad2 endonuclease
IPR006085 XPG, N-terminal
IPR006086 XPG-I domain
IPR029060 PIN-like domain superfamily
IPR001044 XPG/Rad2 endonuclease, eukaryotes
Mapman id Description
14.6.5 DNA damage response.nucleotide excision repair (NER).DNA repair endonuclease (XPG)