Gene: AT3G23100
General Information
Structural Information
- Species Arabidopsis thaliana
- Gene Identifier AT3G23100
- Transcript Identifier AT3G23100.2
- Gene Type Coding gene
- Location Chr3 : 8220721-8221991 : positive
Gene Family Information
- ID HOM05D006635
- #Genes/#Species 121/90
- Phylogenetic origin
- ID ORTHO05D008047
- #Genes/#Species 124/90
- Phylogenetic origin
Gene Duplication Information
Labels
Identifiers
- tid AT3G23100.2
- symbol XRCC4
- full_name homolog of human DNA ligase iv-binding protein XRCC4
- uniprot Q682V0
Descriptions
- Description DNA ligase IV-binding protein
- Computational description homolog of human DNA ligase iv-binding protein XRCC4 (XRCC4); FUNCTIONS IN: protein C-terminus binding; INVOLVED IN: double-strand break repair, metabolic process, DNA recombination; LOCATED IN: nucleus; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Carbamoyl phosphate synthetase, large subunit, ATP-binding (InterPro:IPR005479), DNA double-strand break repair and VJ recombination XRCC4, C-terminal (InterPro:IPR014751), DNA double-strand break repair and VJ recombination XRCC4 (InterPro:IPR010585); BEST Arabidopsis thaliana protein match is: DNA double-strand break repair and VJ recombination XRCC4 (TAIR:AT1G61410.1); Has 189 Blast hits to 182 proteins in 54 species: Archae - 0; Bacteria - 3; Metazoa - 88; Fungi - 4; Plants - 48; Viruses - 0; Other Eukaryotes - 46 (source: NCBI BLink).
- Computational description homolog of human DNA ligase iv-binding protein XRCC4 (XRCC4); FUNCTIONS IN: protein C-terminus binding; INVOLVED IN: double-strand break repair, DNA recombination, metabolic process; LOCATED IN: nucleus; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Carbamoyl phosphate synthetase, large subunit, ATP-binding (InterPro:IPR005479), DNA double-strand break repair and VJ recombination XRCC4, C-terminal (InterPro:IPR014751), DNA double-strand break repair and VJ recombination XRCC4 (InterPro:IPR010585); BEST Arabidopsis thaliana protein match is: DNA double-strand break repair and VJ recombination XRCC4 (TAIR:AT1G61410.1); Has 189 Blast hits to 182 proteins in 54 species: Archae - 0; Bacteria - 3; Metazoa - 88; Fungi - 4; Plants - 48; Viruses - 0; Other Eukaryotes - 46 (source: NCBI BLink).
- Loading (ortholog descriptions from ath)...
Functional Annotation
Biological Process
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0051103 | IBA | Gene Ontology | DNA ligation involved in DNA repair | 1 |
| GO:0006310 | IEA | GOA Database | DNA recombination | |
| GO:0006310 | IEA | InterPro | DNA recombination | |
| GO:0006302 | IEA | GOA Database | double-strand break repair | |
| GO:0006302 | IEA | InterPro | double-strand break repair | |
| GO:0006974 | IEA | GOA Database | cellular response to DNA damage stimulus | |
| GO:0006281 | IEA | GOA Database | DNA repair | |
| GO:0006303 | IBA | Gene Ontology | double-strand break repair via nonhomologous end joining | 1 |
| GO:0051351 | IBA | Gene Ontology | positive regulation of ligase activity | 1 |
| GO:0010165 | IBA | Gene Ontology | response to X-ray | 1 |
Molecular Function
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0003677 | IEA | Gene Ontology | DNA binding | |
| GO:0003677 | IEA | InterPro | DNA binding | |
| GO:0008022 | IPI | Gene Ontology | protein C-terminus binding | 2 |
| GO:0005515 | IPI | Gene Ontology | protein binding | 2 |
| GO:0005524 | IEA | Gene Ontology | ATP binding |
Cellular Component
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0005634 | IEA | GOA Database | nucleus | |
| GO:0005634 | ISM | Gene Ontology | nucleus | |
| GO:0005634 | IEA | InterPro | nucleus | |
| GO:0005958 | IBA | Gene Ontology | DNA-dependent protein kinase-DNA ligase 4 complex | 1 |
| GO:0032807 | IBA | Gene Ontology | DNA ligase IV complex | 1 |
Color Legend
| Experimental Evidence |
| Computational Reviewed Evidence |
| Electronic Evidence |
| Mapman id | Description |
|---|---|
| 14.4.3.2 | DNA damage response.nonhomologous end-joining (NHEJ) repair.LIG4-XRCC4 ligase complex.component XRCC4 |