Gene: AT3G12290

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT3G12290
  • Transcript Identifier AT3G12290.1
  • Gene Type Coding gene
  • Location Chr3 : 3919591-3921326 : positive

Gene Family Information

  • ID HOM05D001290
  • #Genes/#Species 486/98
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT3G12290.1
  • uniprot Q9LHH7

Descriptions

  • Description Amino acid dehydrogenase family protein
  • Computational description Amino acid dehydrogenase family protein; FUNCTIONS IN: binding, catalytic activity; INVOLVED IN: folic acid and derivative biosynthetic process, metabolic process; LOCATED IN: chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain (InterPro:IPR020631), Tetrahydrofolate dehydrogenase/cyclohydrolase (InterPro:IPR000672), NAD(P)-binding domain (InterPro:IPR016040), Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site (InterPro:IPR020867), Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain (InterPro:IPR020630); BEST Arabidopsis thaliana protein match is: Amino acid dehydrogenase family protein (TAIR:AT4G00620.1); Has 9969 Blast hits to 9964 proteins in 2781 species: Archae - 105; Bacteria - 5648; Metazoa - 394; Fungi - 308; Plants - 157; Viruses - 0; Other Eukaryotes - 3357 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009853
IEA
GOA Databasephotorespiration
GO:0008152
IEA
GOA Databasemetabolic process
GO:0006730
IEA
GOA Databaseone-carbon metabolic process
GO:0035999
IBA
IEA
Gene Ontologytetrahydrofolate interconversion1
GO:0046653
IMP
Gene Ontologytetrahydrofolate metabolic process2
GO:0044030
IMP
Gene Ontologyregulation of DNA methylation2

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004488
IEA
GOA Databasemethylenetetrahydrofolate dehydrogenase (NADP+) activity
GO:0004488
IBA
Gene Ontologymethylenetetrahydrofolate dehydrogenase (NADP+) activity1
GO:0004488
IEA
InterPromethylenetetrahydrofolate dehydrogenase (NADP+) activity
GO:0016491
IEA
GOA Databaseoxidoreductase activity
GO:0016787
IEA
GOA Databasehydrolase activity
GO:0003824
IEA
GOA Databasecatalytic activity
GO:0004486
IEA
GOA Databasemethylenetetrahydrofolate dehydrogenase [NAD(P)+] activity
GO:0004477
IEA
GOA Databasemethenyltetrahydrofolate cyclohydrolase activity
GO:0004477
IBA
Gene Ontologymethenyltetrahydrofolate cyclohydrolase activity1

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005829
IDA
GOA Databasecytosol
GO:0005829
HDA
IBA
Gene Ontologycytosol1 3
GO:0009507
IDA
GOA Databasechloroplast
GO:0009507
HDA
ISM
Gene Ontologychloroplast4
GO:0005737
IDA
Gene Ontologycytoplasm2

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR036291 NAD(P)-binding domain superfamily
IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase
Mapman id Description
7.5.7.2 Coenzyme metabolism.tetrahydrofolate metabolism.tetrahydrofolate (THF) interconversions.bifunctional 5,10-methylene-THF dehydrogenase and 5,10-methenyl-THF cyclohydrolase