Gene: AT3G06300

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT3G06300
  • Transcript Identifier AT3G06300.1
  • Gene Type Coding gene
  • Location Chr3 : 1907744-1909675 : positive

Gene Family Information

  • ID HOM05D000373
  • #Genes/#Species 1301/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT3G06300.1
  • symbol P4H2
  • Alias AT-P4H-2,P4H isoform 2
  • full_name prolyl 4-hydroxylase 2
  • uniprot F4JAU3

Descriptions

  • Description P4H isoform 2
  • Computational description P4H isoform 2 (AT-P4H-2); FUNCTIONS IN: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, procollagen-proline 4-dioxygenase activity; INVOLVED IN: peptidyl-proline hydroxylation to 4-hydroxy-L-proline; LOCATED IN: endomembrane system; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Prolyl 4-hydroxylase, alpha subunit (InterPro:IPR006620), Oxoglutarate/iron-dependent oxygenase (InterPro:IPR005123), Metridin-like ShK toxin (InterPro:IPR003582); BEST Arabidopsis thaliana protein match is: 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein (TAIR:AT5G18900.1); Has 2500 Blast hits to 2478 proteins in 341 species: Archae - 0; Bacteria - 386; Metazoa - 1038; Fungi - 78; Plants - 408; Viruses - 17; Other Eukaryotes - 573 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0018401
IDA
IBA
Gene Ontologypeptidyl-proline hydroxylation to 4-hydroxy-L-proline1 2
GO:0080147
IMP
Gene Ontologyroot hair cell development3

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0031418
IEA
Gene OntologyL-ascorbic acid binding
GO:0031418
IEA
InterProL-ascorbic acid binding
GO:0016705
IEA
GOA Databaseoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016705
IEA
InterProoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0005506
IEA
Gene Ontologyiron ion binding
GO:0005506
IEA
InterProiron ion binding
GO:0016491
IEA
GOA Databaseoxidoreductase activity
GO:0046872
IEA
GOA Databasemetal ion binding
GO:0051213
IEA
GOA Databasedioxygenase activity
GO:0004656
IEA
GOA Databaseprocollagen-proline 4-dioxygenase activity
GO:0004656
IDA
IBA
Gene Ontologyprocollagen-proline 4-dioxygenase activity1 2

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005789
IEA
GOA Databaseendoplasmic reticulum membrane
GO:0005783
IEA
GOA Databaseendoplasmic reticulum
GO:0005783
IBA
Gene Ontologyendoplasmic reticulum2
GO:0016020
IEA
GOA Databasemembrane
GO:0016021
IEA
GOA Databaseintegral component of membrane
GO:0005794
IDA
IEA
GOA DatabaseGolgi apparatus
GO:0005794
HDA
Gene OntologyGolgi apparatus4
GO:0005802
IDA
GOA Databasetrans-Golgi network
GO:0005802
HDA
Gene Ontologytrans-Golgi network4
GO:0005768
IDA
GOA Databaseendosome
GO:0005768
HDA
Gene Ontologyendosome4
GO:0000139
IEA
GOA DatabaseGolgi membrane
GO:0000137
HDA
Gene OntologyGolgi cis cisterna5
GO:0005576
ISM
Gene Ontologyextracellular region

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR045054 Prolyl 4-hydroxylase
IPR044862 Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain
IPR006620 Prolyl 4-hydroxylase, alpha subunit
Mapman id Description
18.9.1 Protein modification.hydroxylation.prolyl hydroxylase