Gene: AT3G06110

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT3G06110
  • Transcript Identifier AT3G06110.3
  • Gene Type Coding gene
  • Location Chr3 : 1843517-1844577 : positive

Gene Family Information

  • ID HOM05D001370
  • #Genes/#Species 457/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT3G06110.3
  • symbol MKP2
  • Alias ATMKP2,ARABIDOPSIS MAPK PHOSPHATASE 2,DSPTP1B,DUAL-SPECIFICITY PROTEIN PHOSPHATASE 1B
  • uniprot Q9M8K7

Descriptions

  • Description MAPK phosphatase 2
  • Computational description MAPK phosphatase 2 (MKP2); FUNCTIONS IN: MAP kinase phosphatase activity, protein tyrosine/serine/threonine phosphatase activity; INVOLVED IN: intracellular protein kinase cascade, response to ozone, negative regulation of MAP kinase activity, response to stress; LOCATED IN: nucleus, plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Dual-specific/protein-tyrosine phosphatase, conserved region (InterPro:IPR000387), Dual specificity phosphatase, catalytic domain (InterPro:IPR000340), Dual specificity phosphatase, subgroup, catalytic domain (InterPro:IPR020422); BEST Arabidopsis thaliana protein match is: dual specificity protein phosphatase 1 (TAIR:AT3G23610.2); Has 4028 Blast hits to 4023 proteins in 348 species: Archae - 21; Bacteria - 87; Metazoa - 2101; Fungi - 442; Plants - 308; Viruses - 204; Other Eukaryotes - 865 (source: NCBI BLink).
  • Computational description MAPK phosphatase 2 (MKP2); CONTAINS InterPro DOMAIN/s: Dual-specific/protein-tyrosine phosphatase, conserved region (InterPro:IPR000387), Dual specificity phosphatase, catalytic domain (InterPro:IPR000340), Dual specificity phosphatase, subgroup, catalytic domain (InterPro:IPR020422); BEST Arabidopsis thaliana protein match is: dual specificity protein phosphatase 1 (TAIR:AT3G23610.2).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006470
IBA
IEA
GOA Databaseprotein dephosphorylation
GO:0006470
IEA
InterProprotein dephosphorylation
GO:0043409
IBA
Gene Ontologynegative regulation of MAPK cascade1
GO:0034053
IEA
GOA Databasemodulation by symbiont of host defense-related programmed cell death
GO:0016311
IEA
GOA Databasedephosphorylation
GO:0016311
IEA
InterProdephosphorylation
GO:0035970
IBA
GOA Databasepeptidyl-threonine dephosphorylation
GO:0035335
IBA
GOA Databasepeptidyl-tyrosine dephosphorylation
GO:0043407
IMP
Gene Ontologynegative regulation of MAP kinase activity2
GO:0006979
IMP
Gene Ontologyresponse to oxidative stress2
GO:0010193
IMP
Gene Ontologyresponse to ozone2
GO:0035556
IC
Gene Ontologyintracellular signal transduction2
GO:0034051
IMP
Gene Ontologynegative regulation of plant-type hypersensitive response3
GO:0034599
IMP
Gene Ontologycellular response to oxidative stress3

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004722
IEA
GOA Databaseprotein serine/threonine phosphatase activity
GO:0016787
IEA
GOA Databasehydrolase activity
GO:0004721
IEA
GOA Databasephosphoprotein phosphatase activity
GO:0004721
IBA
Gene Ontologyphosphoprotein phosphatase activity1
GO:0016791
IEA
GOA Databasephosphatase activity
GO:0008138
IEA
GOA Databaseprotein tyrosine/serine/threonine phosphatase activity
GO:0008138
IEA
InterProprotein tyrosine/serine/threonine phosphatase activity
GO:0051019
IBA
GOA Databasemitogen-activated protein kinase binding
GO:0106306
IEA
Gene Ontologyprotein serine phosphatase activity
GO:0106307
IEA
Gene Ontologyprotein threonine phosphatase activity
GO:0005516
IDA
Gene Ontologycalmodulin binding4
GO:0033549
IDA
Gene OntologyMAP kinase phosphatase activity2
GO:0004725
IEA
Gene Ontologyprotein tyrosine phosphatase activity
GO:0005515
IPI
Gene Ontologyprotein binding3
GO:0017017
IBA
Gene OntologyMAP kinase tyrosine/serine/threonine phosphatase activity1
GO:0008330
IBA
Gene Ontologyprotein tyrosine/threonine phosphatase activity1

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
GOA Databasecytoplasm
GO:0005737
IDA
ISM, IBA
Gene Ontologycytoplasm1 3
GO:0005634
IEA
GOA Databasenucleus
GO:0005634
IDA
Gene Ontologynucleus2
GO:0005886
IDA
GOA Databaseplasma membrane
GO:0005886
HDA
Gene Ontologyplasma membrane5

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR020422 Dual specificity protein phosphatase domain
IPR000340 Dual specificity phosphatase, catalytic domain
IPR029021 Protein-tyrosine phosphatase-like
Mapman id Description
18.4.27.1 Protein modification.phosphorylation.protein dual-specifity phosphatase families.MAP-kinase phosphatase