Gene: AT3G02680

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT3G02680
  • Transcript Identifier AT3G02680.1
  • Gene Type Coding gene
  • Location Chr3 : 576378-579226 : positive

Gene Family Information

  • ID HOM05D006560
  • #Genes/#Species 122/95
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT3G02680.1
  • symbol NBS1
  • Alias ATNBS1
  • uniprot Q0H8D7

Descriptions

  • Description nijmegen breakage syndrome 1
  • Computational description nijmegen breakage syndrome 1 (NBS1); CONTAINS InterPro DOMAIN/s: SMAD/FHA domain (InterPro:IPR008984), Forkhead-associated (FHA) domain (InterPro:IPR000253); Has 164 Blast hits to 161 proteins in 63 species: Archae - 0; Bacteria - 2; Metazoa - 112; Fungi - 0; Plants - 40; Viruses - 0; Other Eukaryotes - 10 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007095
IEA
GOA Databasemitotic G2 DNA damage checkpoint signaling
GO:0007095
IBA
Gene Ontologymitotic G2 DNA damage checkpoint signaling1
GO:0007095
IEA
InterPromitotic G2 DNA damage checkpoint signaling
GO:0006302
IEA
GOA Databasedouble-strand break repair
GO:0006302
IEA
InterProdouble-strand break repair
GO:0007049
IEA
GOA Databasecell cycle
GO:0006974
IEA
GOA Databasecellular response to DNA damage stimulus
GO:0006974
IMP
Gene Ontologycellular response to DNA damage stimulus2
GO:0006281
IEA
GOA DatabaseDNA repair
GO:0000724
IMP
IBA
Gene Ontologydouble-strand break repair via homologous recombination1 2
GO:0032508
IBA
Gene OntologyDNA duplex unwinding1
GO:0007131
IMP, IGI
Gene Ontologyreciprocal meiotic recombination2
GO:0007129
IGI
Gene Ontologyhomologous chromosome pairing at meiosis2
GO:0006312
IMP
Gene Ontologymitotic recombination2
GO:0071479
IEP
Gene Ontologycellular response to ionizing radiation3

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Gene Ontologyprotein binding2
GO:0005515
IEA
InterProprotein binding
GO:0003684
IBA
Gene Ontologydamaged DNA binding1

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0030870
IEA
GOA DatabaseMre11 complex
GO:0030870
IBA
Gene OntologyMre11 complex1
GO:0030870
IEA
InterProMre11 complex
GO:0005634
IEA
GOA Databasenucleus
GO:0005634
ISM
Gene Ontologynucleus
GO:0016605
IEA
GOA DatabasePML body

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR000253 Forkhead-associated (FHA) domain
IPR036420 BRCT domain superfamily
IPR008984 SMAD/FHA domain superfamily
IPR040227 Nibrin-related
Mapman id Description
13.3.5.3.1.3 Cell cycle organisation.mitosis and meiosis.meiotic recombination.meiotic double strand break processing.MRE11-RAD50-NBS1 (MRN) complex.component NBS1
14.3.3.3 DNA damage response.homologous recombination repair (HR).DNA resection MRE11-RAD50-NBS1 (MRN) complex.component NBS1