Gene: AT2G44610

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT2G44610
  • Transcript Identifier AT2G44610.1
  • Gene Type Coding gene
  • Location Chr2 : 18411778-18413883 : negative

Gene Family Information

  • ID HOM05D000064
  • #Genes/#Species 3993/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT2G44610.1
  • symbol RAB6A
  • uniprot O80501

Descriptions

  • Description Ras-related small GTP-binding family protein
  • Computational description RAB6A; FUNCTIONS IN: protein binding, GTP binding; INVOLVED IN: secretion by cell; LOCATED IN: plasma membrane, membrane fraction; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Small GTPase (InterPro:IPR020851), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579), Rab6-related (InterPro:IPR015600); BEST Arabidopsis thaliana protein match is: RAB GTPase homolog H1E (TAIR:AT5G10260.1); Has 26612 Blast hits to 26583 proteins in 727 species: Archae - 21; Bacteria - 159; Metazoa - 14143; Fungi - 3598; Plants - 2938; Viruses - 20; Other Eukaryotes - 5733 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0042147
IBA
Gene Ontologyretrograde transport, endosome to Golgi1
GO:0006890
IBA
Gene Ontologyretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum1
GO:0006886
IBA
Gene Ontologyintracellular protein transport1
GO:0015031
IEA
GOA Databaseprotein transport
GO:0016192
IEA
GOA Databasevesicle-mediated transport
GO:0001558
IMP
Gene Ontologyregulation of cell growth2
GO:0006887
IMP
Gene Ontologyexocytosis2
GO:0052324
IMP
Gene Ontologyplant-type cell wall cellulose biosynthetic process2
GO:0032940
IGI
Gene Ontologysecretion by cell3
GO:0006891
IBA
Gene Ontologyintra-Golgi vesicle-mediated transport1

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
GOA Databasenucleotide binding
GO:0005525
IEA
GOA DatabaseGTP binding
GO:0005525
IDA
Gene OntologyGTP binding4
GO:0005525
IEA
InterProGTP binding
GO:0003924
IEA
GOA DatabaseGTPase activity
GO:0003924
IBA
Gene OntologyGTPase activity1
GO:0003924
IEA
InterProGTPase activity
GO:0005515
IPI
Gene Ontologyprotein binding5

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005794
IEA
GOA DatabaseGolgi apparatus
GO:0005794
IDA, HDA
IBA
Gene OntologyGolgi apparatus1 2 6
GO:0012505
IBA
Gene Ontologyendomembrane system1
GO:0005829
IEA
GOA Databasecytosol
GO:0005829
IDA, HDA
Gene Ontologycytosol4 7
GO:0000139
IEA
GOA DatabaseGolgi membrane
GO:0000139
IDA
Gene OntologyGolgi membrane4
GO:0005774
IDA
GOA Databasevacuolar membrane
GO:0005886
IDA
GOA Databaseplasma membrane
GO:0005886
HDA
Gene Ontologyplasma membrane8
GO:0005768
IDA
GOA Databaseendosome
GO:0005768
HDA
Gene Ontologyendosome6
GO:0009506
IDA
GOA Databaseplasmodesma
GO:0009506
HDA
Gene Ontologyplasmodesma9
GO:0005802
IDA
GOA Databasetrans-Golgi network
GO:0005802
HDA
Gene Ontologytrans-Golgi network6
GO:0016020
IEA
GOA Databasemembrane
GO:0016020
IDA
Gene Ontologymembrane3
GO:0005737
IEA
GOA Databasecytoplasm
GO:0000325
HDA
Gene Ontologyplant-type vacuole10

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR027417 P-loop containing nucleoside triphosphate hydrolase
IPR001806 Small GTPase
IPR005225 Small GTP-binding protein domain
Mapman id Description
22.3.4.1.8 Vesicle trafficking.post-Golgi trafficking.vesicle tethering.RAB-GTPase activities.H-class RAB GTPase