Gene: AT2G39800

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT2G39800
  • Transcript Identifier AT2G39800.1
  • Gene Type Coding gene
  • Location Chr2 : 16598516-16602939 : negative

Gene Family Information

  • ID HOM05D001947
  • #Genes/#Species 339/99
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT2G39800.1
  • symbol P5CS1
  • Alias ATP5CS
  • uniprot P54887

Descriptions

  • Description delta1-pyrroline-5-carboxylate synthase 1
  • Computational description delta1-pyrroline-5-carboxylate synthase 1 (P5CS1); FUNCTIONS IN: delta1-pyrroline-5-carboxylate synthetase activity; INVOLVED IN: in 9 processes; LOCATED IN: chloroplast, membrane, cytoplasm; EXPRESSED IN: 6 plant structures; EXPRESSED DURING: C globular stage, D bilateral stage, E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: Glutamate 5-kinase (InterPro:IPR001057), Aspartate/glutamate/uridylate kinase (InterPro:IPR001048), Glutamate 5-kinase, conserved site (InterPro:IPR019797), Aldehyde dehydrogenase, N-terminal (InterPro:IPR016162), Gamma-glutamyl phosphate reductase GPR, conserved site (InterPro:IPR020593), Aldehyde dehydrogenase, C-terminal (InterPro:IPR016163), Aldehyde/histidinol dehydrogenase (InterPro:IPR016161), Delta l-pyrroline-5-carboxylate synthetase (InterPro:IPR005766), Gamma-glutamyl phosphate reductase GPR (InterPro:IPR000965), Aldehyde dehydrogenase (InterPro:IPR015590), Glutamate 5-kinase, ProB-related (InterPro:IPR005715); BEST Arabidopsis thaliana protein match is: delta 1-pyrroline-5-carboxylate synthase 2 (TAIR:AT3G55610.1); Has 14932 Blast hits to 14924 proteins in 2380 species: Archae - 163; Bacteria - 9254; Metazoa - 175; Fungi - 266; Plants - 182; Viruses - 0; Other Eukaryotes - 4892 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006561
IEA
GOA Databaseproline biosynthetic process
GO:0006561
IMP
TAS
Gene Ontologyproline biosynthetic process1 2
GO:0006561
IEA
InterProproline biosynthetic process
GO:0008152
IEA
GOA Databasemetabolic process
GO:0008652
IEA
GOA Databasecellular amino acid biosynthetic process
GO:0016310
IEA
GOA Databasephosphorylation
GO:0042538
IMP, IEP
Gene Ontologyhyperosmotic salinity response2 3
GO:0006979
IMP
Gene Ontologyresponse to oxidative stress2
GO:0055129
IEA
Gene OntologyL-proline biosynthetic process
GO:0009414
IGI, IEP
Gene Ontologyresponse to water deprivation1 4
GO:0048364
IMP
Gene Ontologyroot development2
GO:0009555
IMP
Gene Ontologypollen development5
GO:0009269
IEP
Gene Ontologyresponse to desiccation3
GO:0009651
IEP
Gene Ontologyresponse to salt stress3
GO:0009737
IEP
Gene Ontologyresponse to abscisic acid3

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005524
IEA
GOA DatabaseATP binding
GO:0004350
IBA
IEA
Gene Ontologyglutamate-5-semialdehyde dehydrogenase activity6
GO:0004350
IEA
InterProglutamate-5-semialdehyde dehydrogenase activity
GO:0003824
IEA
GOA Databasecatalytic activity
GO:0003824
IEA
InterProcatalytic activity
GO:0000166
IEA
GOA Databasenucleotide binding
GO:0016740
IEA
GOA Databasetransferase activity
GO:0016491
IEA
GOA Databaseoxidoreductase activity
GO:0016491
IEA
InterProoxidoreductase activity
GO:0016301
IEA
GOA Databasekinase activity
GO:0016620
IEA
GOA Databaseoxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0016620
IEA
InterProoxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0017084
ISS
Gene Ontologydelta1-pyrroline-5-carboxylate synthetase activity1
GO:0004349
IEA
Gene Ontologyglutamate 5-kinase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
GOA Databasecytoplasm
GO:0005737
IDA
ISM
Gene Ontologycytoplasm2
GO:0005737
IEA
InterProcytoplasm
GO:0005739
ISM
Gene Ontologymitochondrion
GO:0009507
IDA
Gene Ontologychloroplast2
GO:0005794
HDA
Gene OntologyGolgi apparatus7

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR036393 Acetylglutamate kinase-like superfamily
IPR016163 Aldehyde dehydrogenase, C-terminal
IPR016162 Aldehyde dehydrogenase, N-terminal
IPR016161 Aldehyde/histidinol dehydrogenase
IPR000965 GPR domain
IPR005766 Delta l-pyrroline-5-carboxylate synthetase
IPR015590 Aldehyde dehydrogenase domain
IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase
IPR001057 Glutamate/acetylglutamate kinase
IPR001048 Aspartate/glutamate/uridylate kinase
Mapman id Description
4.1.1.1.4.1.1 Amino acid metabolism.biosynthesis.glutamate family.glutamate-derived amino acids.proline.main pathway.pyrroline-5-carboxylate synthetase