Gene: AT2G31970

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT2G31970
  • Transcript Identifier AT2G31970.1
  • Gene Type Coding gene
  • Location Chr2 : 13600657-13608815 : positive

Gene Family Information

  • ID HOM05D005045
  • #Genes/#Species 148/94
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT2G31970.1
  • symbol RAD50
  • uniprot Q9SL02

Descriptions

  • Description DNA repair-recombination protein (RAD50)
  • Computational description RAD50; FUNCTIONS IN: zinc ion binding, ATP binding, nuclease activity; INVOLVED IN: DNA repair, double-strand break repair, telomere capping, mitotic recombination, telomere maintenance; LOCATED IN: nucleus, Mre11 complex, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Zinc hook, Rad50 (InterPro:IPR013134), Rad50 zinc hook (InterPro:IPR007517), Recombination/repair protein Rad50 (InterPro:IPR004584); Has 105617 Blast hits to 56308 proteins in 2913 species: Archae - 1820; Bacteria - 19240; Metazoa - 45759; Fungi - 8381; Plants - 4805; Viruses - 470; Other Eukaryotes - 25142 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0051321
IEA
GOA Databasemeiotic cell cycle
GO:0006281
IEA
GOA DatabaseDNA repair
GO:0006281
IEA
InterProDNA repair
GO:0006974
IEA
GOA Databasecellular response to DNA damage stimulus
GO:0007049
IEA
GOA Databasecell cycle
GO:0000723
IEA
GOA Databasetelomere maintenance
GO:0000723
IMP
Gene Ontologytelomere maintenance1
GO:0000723
IEA
InterProtelomere maintenance
GO:0006302
IMP
IBA
Gene Ontologydouble-strand break repair2 3
GO:0006312
IMP
Gene Ontologymitotic recombination4
GO:0016233
IMP
Gene Ontologytelomere capping5
GO:0000722
IBA
Gene Ontologytelomere maintenance via recombination3
GO:0090305
IBA
Gene Ontologynucleic acid phosphodiester bond hydrolysis3
GO:0007004
IBA
Gene Ontologytelomere maintenance via telomerase3
GO:0032508
IBA
Gene OntologyDNA duplex unwinding3
GO:0070192
IBA
Gene Ontologychromosome organization involved in meiotic cell cycle3

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0046872
IEA
GOA Databasemetal ion binding
GO:0016787
IEA
GOA Databasehydrolase activity
GO:0000166
IEA
GOA Databasenucleotide binding
GO:0005524
IEA
GOA DatabaseATP binding
GO:0016887
IEA
InterProATP hydrolysis activity
GO:0051880
IBA
Gene OntologyG-quadruplex DNA binding3
GO:0005515
IPI
Gene Ontologyprotein binding6
GO:0043047
IBA
Gene Ontologysingle-stranded telomeric DNA binding3
GO:0003691
IBA
Gene Ontologydouble-stranded telomeric DNA binding3

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000781
IEA
GOA Databasechromosome, telomeric region
GO:0005634
IEA
GOA Databasenucleus
GO:0005634
IDA
ISM
Gene Ontologynucleus7
GO:0005634
IEA
InterPronucleus
GO:0005694
IEA
GOA Databasechromosome
GO:0030870
IEA
GOA DatabaseMre11 complex
GO:0030870
IBA
TAS
Gene OntologyMre11 complex3 7
GO:0030870
IEA
InterProMre11 complex
GO:0005737
IDA
Gene Ontologycytoplasm7
GO:0000794
IBA
Gene Ontologycondensed nuclear chromosome3

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR027417 P-loop containing nucleoside triphosphate hydrolase
IPR004584 DNA repair protein Rad50, eukaryotes
IPR013134 RAD50, zinc hook
IPR038729 Rad50/SbcC-type AAA domain
Mapman id Description
13.3.5.3.1.2 Cell cycle organisation.mitosis and meiosis.meiotic recombination.meiotic double strand break processing.MRE11-RAD50-NBS1 (MRN) complex.component RAD50
14.3.3.2 DNA damage response.homologous recombination repair (HR).DNA resection MRE11-RAD50-NBS1 (MRN) complex.component RAD50